This study reflects on the recognised need for more joined-up, high-quality research on phytotherapy that addresses the current societal challenges in finding alternatives to the use of antibiotics. The study applied a multidisciplinary participatory approach in an expert workshop exercise within the FP7 EU IMPRO project. Prior to this study, a literature review was elaborated on research in the field of phytotherapy as applied to farm animals, cooperation between research bodies and initiatives to reduce the use of antibiotics by using phytotherapeutic remedies. The review was delivered to the participants of the workshop so as to receive feedback on it and enrich the discussion. Different expertise, background in research or veterinary practice, and varying positions regarding phytotherapy were the criteria in targeting participants. A structured workshop was subsequently organised, with questions to experts addressing scientific validation of phytotherapy, effective treatment under farm conditions and necessary developments for the future. Challenges identified by the experts were as follows: poor study designs, lack of reproducibility of studies, poor standardisation of products, cost-benefit concerns, lack of veterinarian training and poor data availability. To overcome obstacles, the need for improved study designs for clinical trials was given priority in order to prove the efficacy of remedies and to implement a monitoring system which enables the assessment of the effectiveness of treatments in farm practice. Reflections in this report are intended to be a resource for scientists, policy makers and end users for an effective use of phytotherapy at farm level.
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http://dx.doi.org/10.3389/fvets.2017.00248 | DOI Listing |
J Cosmet Dermatol
January 2025
Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: Skin aging is a multifaceted condition marked by the development of wrinkles, reduced suppleness, and uneven pigmentation. Both endogenous and exogenous factors contribute to skin aging. Studies have examined the possible anti-aging advantages of horsetail and soybean extracts, which are abundant in antioxidants.
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December 2024
Laboratory of Cell Biology and Neurobiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.
Glioblastoma multiforme (GBM) is one of the most aggressive and difficult-to-treat brain tumors, with a poor prognosis due to its high resistance to conventional therapies. Current treatment options, including surgical resection, radiotherapy, and chemotherapy, have limited effectiveness in improving long-term survival. Despite the emergence of new therapies, monotherapy approaches have not shown significant improvements, highlighting the need for innovative therapeutic strategies.
View Article and Find Full Text PDFDiseases
December 2024
Department of Radiology, King Fahd Armed Forces Hospital, Jeddah 23311, Saudi Arabia.
() is a Gram-negative, spiral-shaped bacterium that colonizes the gastric epithelium and is associated with a range of gastrointestinal disorders, exhibiting a global prevalence of approximately 50%. Despite the availability of treatment options, frequently reemerges and demonstrates increasing antibiotic resistance, which diminishes the efficacy of conventional therapies. Consequently, it is imperative to explore non-antibiotic treatment alternatives to mitigate the inappropriate use of antibiotics.
View Article and Find Full Text PDFBiomed Pharmacother
December 2024
Structural Biology Laboratory, Oswaldo Cruz Institution, Fiocruz, Rio de Janeiro, Brazil; Programa de Pós-graduação em Biologia Celular e Molecular, Oswaldo Cruz Institution, Fiocruz, Rio de Janeiro, Brazil. Electronic address:
Trichomoniasis, a globally prevalent sexually transmitted infection caused by Trichomonas vaginalis, affects approximately 278 million people each year. It presents a challenge due to resistance to the current treatment, Metronidazole (MTZ), which is also associated with side effects. Cannabis sativa, with more than 100 phytocannabinoids and numerous studies for therapeutic applications, including parasitic infections, has undergone a significant shift in acceptance worldwide, highlighted by legalizations and substantial revenue projections.
View Article and Find Full Text PDFJ Med Food
December 2024
Escola de Artes, Ciências e Humanidades, University of São Paulo (EACH-USP), São Paulo, Brazil.
Stingless bee honey is a natural product consisting of sugars, organic acids, proteins, minerals, vitamins, phenolic compounds, and flavonoids. Due to its healing properties, honey is often used in phytotherapy and for homemade syrups. The search for natural therapeutic alternatives has been an increasing trend in recent years, mainly due to the side effects of artificial drugs and increasing antibiotic resistance.
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