AI Article Synopsis
- Researchers synthesized low toxic graphene quantum dots (GQD) from citric acid and analyzed them using various techniques like UV-vis spectroscopy and X-ray diffraction.
- GQD was employed to enhance the electro-oxidation of doxorubicin (DOX) at a lower voltage (-0.56 V) when applied to a glassy carbon electrode, outperforming standard electrodes.
- The study demonstrated that GQD improves the electron-transfer reaction for DOX, indicating its potential as a highly effective electrochemical sensor in detecting DOX in solution.
Article Abstract
Low toxic graphene quantum dot (GQD) was synthesized by pyrolyzing citric acid in alkaline solution and characterized by ultraviolet--visible (UV-vis) spectroscopy, X-ray diffraction (XRD), atomic force microscopy (AFM), spectrofluorimetery and dynamic light scattering (DLS) techniques. GQD was used for electrode modification and electro-oxidation of doxorubicin (DOX) at low potential. A substantial decrease in the overvoltage (-0.56 V) of the DOX oxidation reaction (compared to ordinary electrodes) was observed using GQD as coating of glassy carbon electrode (GCE). Differential pulse voltammetry was used to evaluate the analytical performance of DOX in the presence of phosphate buffer solution (pH 4.0) and good limit of detection was obtained by the proposed sensor. Such ability of GQD to promote the DOX electron-transfer reaction suggests great promise for its application as an electrochemical sensor.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762600 | PMC |
| http://dx.doi.org/10.1016/j.jpha.2016.03.003 | DOI Listing |
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