Scott, DJ, Ditroilo, M, and Marshall, P. Effect of accommodating resistance on the post-activation potentiation response in rugby league players. J Strength Cond Res 32(9): 2510-2520, 2018-This study examined the postactivation potentiation (PAP) response of 2 conditioning activities (CA), the hex bar deadlift and back squat, combined with accommodating resistance; this adds a percentage of the total resistance during the exercise. Twenty amateur rugby league players performed 2 experimental trials and a control trial without a CA. Participants performed a countermovement jump (CMJ) before and 30, 90, and 180 seconds after 1 set of 3 repetitions of each CA at 70% 1 repetition maximum (RM), with up to an additional 23% 1RM from accommodating resistance. Peak power output (PPO), force at PPO, velocity at PPO, and jump height were calculated for each CMJ. Surface electromyography (EMG) of the vastus lateralis (VL), rectus femoris (BF), tibialis anterior (TA), and gastrocnemius medialis (GM) was also measured. Repeated-measures analysis of variance revealed no significant (p > 0.05) PAP response for either exercise condition when comparing CMJ variables with baseline values nor were there any significant (p > 0.05) differences between exercise conditions. However, individualized recovery intervals (baseline vs. maximum potentiation response) demonstrated significant (p ≤ 0.05) improvements in PPO (3.99 ± 4.99%), force at PPO (4.87 ± 6.41%), velocity at PPO (4.30 ± 5.86%), jump height (8.45 ± 10.08%), VL EMG (20.37 ± 34.48%), BF EMG (22.67 ± 27.98%), TA EMG (21.96 ± 37.76%), and GM EMG (21.89 ± 19.65%). Results from this study must be interpreted with caution; however, it is conceivable that athletic performance can be acutely enhanced when complex training variables are individualized.
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Ovarian clear cell carcinoma (OCCC) accounts for ~10% of all epithelial ovarian cancers and is considered a different entity from the more common high-grade serous ovarian carcinoma (HGSC), with distinct clinical presentations, different risk, and prognostic factors, and specific molecular features. Most OCCCs are diagnosed at an early stage and show favorable outcomes, in contrast to those diagnosed at advanced stages, which exhibit intrinsic resistance to platinum-based chemotherapy regimens and a very poor prognosis. The standard treatment of advanced OCCC is currently based on primary debulking surgery followed by platinum-based chemotherapy according to recent international guidelines.
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