In this paper we present the coreferential tagging of part of the EPEC Corpus of Basque. Although coreference is a pragmatic linguistic phenomenon highly dependent on the situational context, it shows some language-specific patterns that vary according to the features of each language. Due to the fact that Basque is not an Indo-European language, it differs considerably in grammar from the languages spoken in surrounding areas. We will explain these features and the decisions made in each case. After describing the criteria defined for coreferential tagging in Basque, the annotation process will be explained. Our annotation is based on a morphologically and syntactically annotated corpus that provides us with a manageable environment, in which the specific structures that are part of a reference chain can be more easily identified. A part of the corpus was tagged by two annotators who marked up the same text independently, and by another annotator that acted as judge, solving problems in case of disagreement. All this process has been automatized as a result of previous studies carried out in this field. The automatic detection of mentions (Soraluze et al., in: Proceedings of Konvens, 2012) has provided us with a better working environment, and given us the possibility to build a first significant corpus for a later computational treatment of automatic coreferential resolution.
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Sci Rep
December 2024
Department of Pharmacology, University of the Basque Country, UPV/EHU, Sarriena S/N, 48940, Leioa, Bizkaia, Spain.
Cannabis use disorder affects up to 42% of individuals with schizophrenia, correlating with earlier onset, increased positive symptoms, and more frequent hospitalizations. This study employed an untargeted lipidomics approach to identify biomarkers in plasma samples from subjects with schizophrenia, cannabis use disorder, or both (dual diagnosis), aiming to elucidate the metabolic underpinnings of cannabis abuse and schizophrenia development. The use of liquid chromatography-high resolution mass spectrometry enabled the annotation of 119 metabolites, with the highest identification confidence level achieved for 16 compounds.
View Article and Find Full Text PDFOpen Res Eur
April 2024
AZTI, Marine Research, Basque Research and Technology Alliance (BRTA), Sukarrieta, Spain.
Background: The Atlantic mackerel, (Linnaeus, 1758) is a commercially valuable migratory pelagic fish inhabiting the northern Atlantic Ocean and the Mediterranean Sea. Given its highly migratory behaviour for feeding and spawning, several studies have been conducted to assess differentiation among spawning components to better define management units, as well as to investigate possible adaptations to comprehend and predict recent range expansion northwards.
Methods: Here, a high-quality genome of was sequenced and annotated, as an increasing number of population genetic studies have proven the relevance of reference genomes to investigate genomic markers/regions potentially linked to differences at finer scale.
Glia
February 2025
Glial Cell Biology Lab, Achucarro Basque Center for Neuroscience, Leioa, Spain.
Phagocytosis is an indispensable function of microglia, the brain professional phagocytes. Microglia is particularly efficient phagocytosing cells that undergo programmed cell death (apoptosis) in physiological conditions. However, mounting evidence suggests microglial phagocytosis dysfunction in multiple brain disorders.
View Article and Find Full Text PDFComput Methods Programs Biomed
December 2024
Department of Computer Science and Artificial Intelligence, Universidad de Granada, Granada, Spain. Electronic address:
Background: Currently, prostate cancer (PCa) diagnosis relies on the human analysis of prostate biopsy Whole Slide Images (WSIs) using the Gleason score. Since this process is error-prone and time-consuming, recent advances in machine learning have promoted the use of automated systems to assist pathologists. Unfortunately, labeled datasets for training and validation are scarce due to the need for expert pathologists to provide ground-truth labels.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
October 2024
Gastrointestinal Genetics Lab, CIC bioGUNE - BRTA, Derio, Spain; Ikerbasque, Basque Foundation for Science, Bilbao, Spain; Department of Medicine and Surgery, LUM University, Casamassima, Italy. Electronic address:
Background & Aims: Limiting the dietary intake of certain carbohydrates has therapeutic effects in some but not all irritable bowel syndrome (IBS) patients. We investigated genetic variation in human Carbohydrate-Active enZYmes (hCAZymes) genes in relationship to the response to a FODMAP-lowering diet in the DOMINO study.
Methods: hCAZy polymorphism was studied in patients with IBS from the dietary (FODMAP-lowering; n = 196) and medication (otilonium bromide; n = 54) arms of the DOMINO trial via targeted sequencing of 6 genes of interest (AMY2B, LCT, MGAM, MGAM2, SI, and TREH).
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