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Proteomic analysis of Trichoderma harzianum secretome and their role in the biosynthesis of zinc/iron oxide nanoparticles.
Sci Rep
January 2025
Instituto de Investigaciones en Biodiversidad y Biotecnología (INBIOTEC-CONICET), Fundación para Investigaciones Biológicas Aplicadas (FIBA), Mar del Plata, 7600, Argentina.
The fungal green synthesis of nanoparticles (NPs) has gained great interest since it is a cost-effective and easy handling method. The process is simple because fungi secrete metabolites and proteins capable of reducing metal salts in aqueous solution, however the mechanism remains largely unknown. The aim of this study was to analyze the secretome of a Trichoderma harzianum strain during the mycobiosynthesis process of zinc and iron nanoparticles.
View Article and Find Full Text PDFAnxiety of microbially synthesized FeO-SPIONs on embryonic/larval ontogeny in red tilapia (Oreochromis sp.).
Appl Microbiol Biotechnol
January 2025
National Institute of Oceanography and Fisheries (NIOF), Cairo, Egypt.
Iron oxide nanoparticles, recognized for their superparamagnetic properties, are promising for future healthcare therapies. However, their extensive use in medicine and electronics contributes to their discharge into our environments, highlighting the need for further research on their cellular damage effects on aquatic organisms. While the detrimental properties of other compounds have been stated in the early-life stages of fish, the cytotoxic consequences of superparamagnetic iron oxide nanoparticles (SPIONs) in these stages are still unexplored.
View Article and Find Full Text PDFBioactive Macromolecule-mediated Biogenic FeONPs Attenuate Inflammation in Atherosclerotic Rat by Activating PI3K/Akt/eNOS Pathway.
Curr Pharm Des
September 2024
Department of Cardiology, The Fourth People's Hospital of Jinan, Shifan Road, No. 50, Jinan 250031, China.
Article Synopsis
- Atherosclerosis is characterized by the thickening and hardening of artery walls, and this study explored using eco-friendly iron oxide nanoparticles (FeONPs) infused with curcumin to reduce inflammation in a rat model.
- The synthesis of these nanoparticles was examined for their antioxidant properties against harmful free radicals, and the impact on gene expression related to inflammation and vascular health was analyzed using RT-PCR.
- Results showed that the FeONPs exhibited strong antioxidative effects and increased gene expression (eNOS, PI3K, AKT) in a dose-dependent manner, although there were no significant differences observed between the control groups in gene expression.
Exploring novel potential of mycosynthesized magnetic nanoparticles for phosphatase immobilization and biological activity.
Int J Biol Macromol
November 2024
Department of Biotechnology, Central University of Haryana, Jant-Pali, Mahendergarh 123031, Haryana, India; Laboratory of Bioprocess Technology, Department of Microbiology, Maharshi Dayanand University, Rohtak 124001, Haryana, India. Electronic address:
Among different microbes, fungi are proficient candidates for the extracellular synthesis of iron nanoparticles. For biogenic synthesis of iron nanoparticles, a thermophilic mould Myceliophthora thermophila BJTLRMDU7 was used in this study. Mycogenic magnetic nanoparticles were used for phosphatase immobilization and therapeutic applications such as antimicrobial and antimalarial activity.
View Article and Find Full Text PDFSelective Gas-Phase Depletion of Chemical Contaminants in Dissolved Organic Matter Increases Compositional Coverage by FT-ICR Mass Spectrometry.
J Am Soc Mass Spectrom
October 2024
National High Magnetic Field Laboratory, Florida State University,1800 East Paul Dirac Drive, Tallahassee, Florida 32310-4005, United States.
Fourier transform ion cyclotron resonance mass spectrometry of dissolved organic matter (DOM) extracted from environmental samples provides molecular speciation that enables visualization of compositional trends in the fate and cycling of biogenic and anthropogenic organics. Often, chemical contamination is introduced during field sampling (i.e.
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