A 59-year-old woman attended a previous hospital complaining of a nodule of the right axilla. Although ultrasonography had shown no evidenceof malignancy, a growth of thenodulewas found on follow-up. Excisional biopsy revealed a primary accessory breast cancer. Because the resected margins were involved, she was referred to our hospital for additional treatment. Based on imaging, both bilateral mammary glands and axillary lymph nodes were reported normal, and distant metastasis was not observed. We performed additional resection of the right axillary tissue around the biopsy site and the right axillary lymph nodedisse ction. Histo-pathological examination revealed the residual invasive ductal carcinoma in the resected specimen. Both the new surgical margins and the lymph nodes were free of disease. Accessory breast cancer is relatively rare, with the incidence being less than 1% of all breast cancers. It is most frequent in the axillary region. Local extensive resection with sufficient surgical margin and axillary lymph node dissection are generally required. This case report presents our clinical experience of accessory breast cancer with some discussion of the literature.
Download full-text PDF |
Source |
---|
J Cardiothorac Surg
December 2024
Centre for Human Anatomy Education, Department of Anatomy and Developmental Biology, Biomedical Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Australia.
Arterial variations in the upper limb are of significant clinical importance, especially in procedures such as venepunctures, coronary artery bypass grafts, trauma reconstructive surgeries, brachial plexus nerve blocks, and breast reconstructions. This report presents previously undocumented arterial variations in the upper limbs in a 95-year-old female cadaveric donor. We observed bilateral superficial ulnar arteries originating at the cubital fossa, deviating from the previously reported origin at the proximal brachial artery.
View Article and Find Full Text PDFDiagnostics (Basel)
November 2024
Clinic of Surgical Semiotics and Thoracic Surgery-1, Department IX-Surgery-1, "Victor Babes" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Accessory breast cancer cases are rarely reported in the literature. Of the reported cases, the predominantly available ones are those localized in the axillary region. We present here a very rare case of metastatic accessory breast cancer.
View Article and Find Full Text PDFInt J Surg Case Rep
November 2024
Department of Surgery, School of Medicine, Collage of Health Sciences, Salale University, Fiche, Ethiopia. Electronic address:
Introduction: Accessory breast tissue is a rare condition occurring in 1-3 % of males, primarily in the bilateral axillary region. Kajava Class I accessory breast, characterized by glandular tissue, an areola, and a nipple, is rarely reported. This case report highlights the clinical presentation, diagnostic approach, and management of this rare entity in an elderly male.
View Article and Find Full Text PDFFront Cell Infect Microbiol
December 2024
Department of breast surgery, Shanxi Cancer Hospital, Taiyuan, Shanxi, China.
Background: Elevated evidence suggests that KIF20A plays an important role in hepatocellular carcinoma (HCC) progression. Nevertheless, the underlying mechanism by which KIF20A promotes HCC cell growth are not well understood.
Methods: Using TCGA-LIHC RNAseq and GEO datasets, we assessed the KIF20A expression and patient survival in HCC and hepatitis B virus (HBV)-related HCC.
Int J Mol Sci
November 2024
Institute of Physiological Chemistry, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
It has been previously established that breast cancer cells exhibit high expression of the monocarboxylate (lactate) transporters (MCT1 and/or MCT4) and carbonic anhydrase IX (CAIX) and form a functional metabolon for proton-coupled lactate export, thereby stabilizing intracellular pH. CD147 is the MCT accessory protein that facilitates the creation of the MCT/CAIX complex. This study describes how the small molecule Beta-Galactose 2C (BGal2C) blocks the physical and functional interaction between CAIX and either MCT1 or MCT4 in Xenopus oocytes, which reduces the rate of proton and lactate flux with an IC of ~90 nM.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!