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Correlates of Perceived Illness Severity and Terminality in Advanced Lung and Prostate Cancer.
J Pain Symptom Manage
January 2025
Department of Psychology, Indiana University Indianapolis, Indianapolis, Indiana, USA. Electronic address:
Context: While prognostic awareness has been commonly assessed as perceived illness terminality in patients with advanced cancer, both perceptions of illness severity and terminality may be correlated with symptom burden and quality of life.
Objectives: The present study examined physical and psychological symptoms, quality of life, and smoking status in relation to perceived illness severity and terminality in patients with advanced, inoperable lung and prostate cancer.
Methods: Patients (N=198) were recruited from hospitals in the midwestern U.
Progressive Cachexia: Tuberculosis, Cancer, or Thyrotoxicosis? Disease-Directed Therapy and Atypical Courses of Autoimmune and Malignant Thyroid Diseases in a High Specialization Era: Case-Control Study with a Critical Literature Review.
Biomedicines
November 2024
Department of Pharmacognosy and Herbal Medicines, Wroclaw Medical University, 50-367 Wrocław, Poland.
Critical and progressive cachexia may be observed in numerous medical disciplines, but in patients with various diseases, several pathways overlap (endocrine, inflammatory and kidney diseases, heart failure, cancer). Unlike numerous cohort studies that examine thyroid cancer and risk factors, a different method was used to avoid bias and analyze the sequence of events, i.e.
View Article and Find Full Text PDFBecoming Housed During Palliative Care Enrollment: Identifying Drivers, Deterrents, and Directions for Future Care.
Int J Environ Res Public Health
November 2024
Palliative Care Training Center, University of Washington, Seattle, WA 98195, USA.
Homelessness is associated with accelerated disease progression, and housing placements are less likely when experiencing serious illness. Little research to date has focused on how to successfully secure housing placement during serious illness and end of life. This study aimed to address this gap by examining factors influencing housing placement among seriously ill palliative care patients experiencing homelessness.
View Article and Find Full Text PDFPalliative care improves the quality of life for seriously ill patients, but misconceptions and knowledge gaps hinder its implementation in home healthcare (HHC). This study developed and pilot-tested HHC-specific questionnaires to measure palliative care knowledge, attitudes, and confidence (PC-KAC) among clinicians, patients, and caregivers. Using literature reviews, expert input, and cognitive interviews, the questionnaires were refined to ensure clarity, practical relevance, and content validity.
View Article and Find Full Text PDFEfficacy and Safety of Continuous vs Intermittent Linezolid Infusion in Critically Ill Patients with Septic Shock.
Indian J Crit Care Med
December 2024
Department of Anesthesia and ICU, Ain Shams University, Cairo, Egypt.
Unlabelled: The synthetic antimicrobial agent Linezolid effectively penetrates many tissues and exhibits effectiveness against drug-resistant Gram-positive bacteria. This agent's pharmacokinetic qualities cast doubt on the need for intravenous treatment in cases of serious illness. For its time-dependent action to have an impact, serum levels must stay above the minimum inhibitory concentration throughout the dosage interval.
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