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Hepatic pseudolymphoma: imaging features on dynamic contrast-enhanced MRI and diffusion-weighted imaging. | LitMetric

AI Article Synopsis

  • The study aimed to analyze MRI features of hepatic pseudolymphoma using dynamic contrast-enhanced (DCE) MR imaging and diffusion-weighted imaging (DWI) in 14 patients.
  • A total of 20 lesions were assessed, revealing that all lesions had round contours, sizes averaging 1.3 cm, and specific signal characteristics on T1- and T2-weighted images.
  • Key findings included hypervascular lesions with lower signal intensity compared to the portal vein and lower apparent diffusion coefficient (ADC) values than the spleen, suggesting distinct MRI patterns for hepatic pseudolymphoma.

Article Abstract

Purpose: To investigate dynamic contrast-enhanced (DCE) MR findings and diffusion-weighted imaging (DWI) characteristics of hepatic pseudolymphoma.

Materials And Methods: The MR data of 20 lesions in 14 patients with histopathologically proven hepatic pseudolymphoma were retrospectively analyzed. All patients underwent dynamic gadopentetate dimeglumine-enhanced MR imaging and DWI. Morphologic characteristics and signal features on T1- and T2-weighted images (T1WI, T2WI), and DCE pattern were qualitatively evaluated. The quantitative analysis was performed for the size, the degree of enhancement on arterial phase, signal intensity (SI) of DWI, and apparent diffusion coefficient (ADC) values. The Wilcoxon signed ranks test was used for statistical analysis.

Results: The contour of all lesions was round. The lesion size was 0.7-2.8 cm (mean 1.3 ± 0.5 cm). All lesions manifested as homogeneous hypointensity on T1WI and hyperintensity on T2WI. All lesions were shown as hypervascular with various enhancement patterns on DCE MR imaging. The presence of peripheral enhancement and pseudocapsule was observed in 7 and 4 lesions, respectively. SI of the hepatic pseudolymphoma was significantly lower than that of portal vein on arterial phase (P < 0.001) and the ADC was significantly lower than that of spleen (P = 0.012).

Conclusion: A homogeneous nodule with small size (<2 cm), manifestation of hypervascular with lower SI than that of portal vein on arterial phase and lower ADC values than that of spleen are the common MR features of hepatic pseudolymphoma.

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Source
http://dx.doi.org/10.1007/s00261-018-1468-5DOI Listing

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