Sensorineural Hearing Loss in Selective Immunglobulin A Deficiency.

Turk Arch Otorhinolaryngol

Department of Otorhinolaryngology, Başkent University Adana Hospital, Adana, Turkey.

Published: March 2017

Objective: To assess hearing functions in pediatric patients with selective immunoglobulin A (IgA) deficiency (SIGAD).

Methods: Pure-tone audiometry, acoustic impedance, otoacoustic emission, and brainstem audiometric measurements were taken during a non-infectious period in 28 patients with SIGAD and 28 healthy children with normal otoscopic examination. The results of the hearing tests were compared between the two groups.

Results: Two male patients and one female patient in the SIGAD group were found to have sensorineural hearing loss (SNHL). However, a comparison of the average pure tone cut-off values at 0.5, 1, 2, and 4 kHz did not reveal any statistically significant difference between the groups (p>0.05).

Conclusion: Pediatric patients with SIGAD may exhibit SNHL at certain frequencies and require follow-up for the potential development of hearing loss.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782926PMC
http://dx.doi.org/10.5152/tao.2017.1923DOI Listing

Publication Analysis

Top Keywords

hearing loss
12
sensorineural hearing
8
pediatric patients
8
patients sigad
8
loss selective
4
selective immunglobulin
4
immunglobulin deficiency
4
deficiency objective
4
objective assess
4
hearing
4

Similar Publications

Unlabelled: Using the UK Clinical Practice Research Datalink, our cohort study matched 237,297 individuals with hearing loss (HL) to 829,431 without HL. The study found an 8-10% higher risk of major osteoporotic fracture in individuals with HL compared to those without. Additionally, within the HL cohort, we identified risk factors for potential inclusion in fracture risk models.

View Article and Find Full Text PDF

The noise exposure levels of workers wearing hearing protective devices (HPDs) depend on ambient noise and the protective effect of hearing protectors. This cross-sectional study aimed to adjust for cumulative noise exposure (CNE) based on the effective protection of hearing protection devices and explore the dose-response relationship between noise-induced hearing loss (NIHL) and adjusted cumulative noise exposure. A questionnaire was used to acquire the basic characteristics and occupational information of noise-exposed workers.

View Article and Find Full Text PDF

The inferior colliculus is a key nucleus in the central auditory pathway, integrating acoustic stimuli from both cochleae and playing a crucial role in sound localization. It undergoes functional and structural development in childhood and experiences age-related degeneration later in life, contributing to the progression of age-related hearing loss. This study aims at finding out, whether the volume of the human inferior colliculus can be determined by analysis of routinely performed MRIs and whether there is any age-related variation.

View Article and Find Full Text PDF

Objectives: Hearing impairment during childhood is a widespread health issue. Prompt recognition and timely intervention are vital for the advancement of language skills. Insufficient parental knowledge can lead to a delay in diagnosing and treating a condition, which can have a negative impact on academic performance.

View Article and Find Full Text PDF

Cochlear Organ Dissection, Immunostaining, and Confocal Imaging in Mice.

Bio Protoc

January 2025

ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.

The organ of Corti, located in the inner ear, is the primary organ responsible for animal hearing. Each hair cell has a V-shaped or U-shaped hair bundle composed of actin-filled stereocilia and a kinocilium supported by true transport microtubules. Damage to these structures due to noise exposure, drug toxicity, aging, or environmental factors can lead to hearing loss and other disorders.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!