We report a case of a bodybuilder who took a regimen of anabolic steroids containing stanozolol and testosterone propionate for 8 weeks which led to the development of jaundice and severe pruritus with serum total bilirubin reaching 41.22 mg/dL. Despite supportive care with fluid and albumin therapy, serum creatinine was progressively increasing. He underwent 6 successful sessions of plasma exchange (PE) with marked improvement at the end of the sessions. Three months after discharge, the patient's creatinine and total bilirubin levels were 1.08 mg/dL and 1.2 mg/dL, respectively.
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http://dx.doi.org/10.1155/2017/4296474 | DOI Listing |
Steroids
December 2024
School of Health Sciences, Ariel University, Israel. Electronic address:
Purpose: This study examined the effect of resistance training (RT) by itself and in combination with supraphysiological administration of nandrolone decanoate (ND) on the inflammatory, apoptotic, and oxidative stress response in cardiac tissue. The effect of the training and androgen intervention on adiponectin expression, a potential cardio protectant was also examined.
Methods: Forty male C57Bl/6J mice, 3 months of age were randomized into four groups (n = 10 per group).
Steroids
December 2024
Department of Health Sciences, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. Electronic address:
Introduction: The use of anabolic steroids is widely adopted for aesthetic purposes and sports performance. In supraphysiological doses, they can impair various physiological systems. However, we know little about their effects on the heart, especially when combined with strength training.
View Article and Find Full Text PDFDrug Test Anal
December 2024
Catalonian Antidoping Laboratory, Doping Control Research Group, Hospital del Mar Research Institute, Barcelona, Spain.
The detection of endogenous anabolic androgenic steroids misuse in Asian population using the Steroidal Module of the Athlete Biological Passport (ABP) is a challenge due to the high prevalence of UGT2B17 gene deletion polymorphism with low levels of testosterone (T) glucuronide. In this study, the capabilities of different approaches based on urine analysis for the detection of oral T undecanoate administration were evaluated in 13 Asian volunteers, including 11 subjects with del/del genotype and 2 subjects with del/ins genotype. In the first part of the work, the effect on the urinary steroid profile (SP) and on the isotope ratio mass spectrometry markers was evaluated.
View Article and Find Full Text PDFDrug Test Anal
December 2024
Anti-Doping Laboratory, LSI Medience Corporation, Tokyo, Japan.
The detection of endogenous anabolic androgenic steroids misuse in Asian population using the Steroidal Module of the Athlete Biological Passport (ABP) is a challenge due to the high prevalence of UGT2B17 gene deletion polymorphism and low levels of testosterone (T) glucuronide. In this study, the capabilities of different approaches based on urine analysis for detecting oral T undecanoate administration were evaluated in 13 Asian volunteers, including 11 subjects with del/del genotype and 2 subjects with del/ins genotype. In this part of the work, the effect on the urinary steroid profile (SP) and the isotope ratio mass spectrometry (IRMS) markers were studied.
View Article and Find Full Text PDFNordisk Alkohol Nark
December 2024
Professor, Department of Welfare, Management and Organisation, Østfold University College, Halden, Norway.
Research has identified the use of anabolic-androgenic steroids (AAS) as a gap between treatment needs and available facilities for substance use disorder (SUD) treatment in Norway. State policy emphasizes the need for measures to ensure coordinated treatment services. This study aims to explore whether clinical pathways of mental health and substance abuse and team-based organisation function as intended in the treatment of patients with AAS use.
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