Objective: The aim of this research was to determine the association between the polymorphism and uterine leiomyomas.
Material And Methods: For genotyping the polymorphism of the vitamin D receptor, real-time polymerase chain reaction was performed on blood samples of uterine leiomyoma (n=27) and control (n=33) groups. For statistical analyses, SPSS v.23 software (SPSS Inc., Chicago, IL, USA) was used.
Results: A statistically significant difference was observed for the frequency of the CC genotype between the uterine leiomyoma and control groups, and the frequencies of the T allele in the uterine leiomyoma groups were significantly higher than in the control group.
Conclusion: The presence of the CC genotype may be a risk-reducing factor and the T allele may be a potential risk factor for developing uterine leiomyoma.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085526 | PMC |
| http://dx.doi.org/10.4274/jtgga.2018.0002 | DOI Listing |
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