AI Article Synopsis

  • Iatrogenic acute aortic dissection (IAAD) can occur during cardiac surgery, with a low incidence of 0.04%, but it leads to worse outcomes compared to spontaneous cases.
  • A 64-year-old man experienced chest tightness and underwent off-pump coronary artery bypass grafting (OPCABG), which resulted in IAAD and necessitated emergency surgery and support from ECMO.
  • Despite the removal of ECMO and stabilization of his leg condition, the patient ultimately died from uncontrollable sepsis 18 days post-surgery, underscoring the severe risks involved with OPCABG and the uncertain role of ECMO in IAAD management.

Article Abstract

Rationale: Iatrogenic acute aortic dissection (IAAD) induced by cardiac surgery is a fatal complication, with 0.04% of therapeutic procedures and worse outcomes than spontaneous aortic dissection.

Patients Concerns: A 64-year-old male complaining of intermittent chest tightness for 4 years received an off-pump coronary artery bypass grifting (OPCABG) and IAAD was found during surgery.

Diagnosis: Unstable angina, coronary artery triple vessel lesion, IAAD.

Interventions: An ascending aorta replacement surgery was implemented immediately and extracorporeal membrane oxygenation (ECMO) was applied during surgery. The patient suffered from oliguria symptoms and began to receive continuous renal replacement therapy (CRRT) after surgery. What was worse, osteofascial compartment syndrome (OCS) was also confirmed the day after surgery.

Outcomes: The CRRT and ECMO were both removed and the condition of the right leg was also stable. But the patient passed away because of uncontrollable sepsis 18 days after the surgery.

Lessons: OPCABG is clearly the riskiest type of surgery associated with IAADs in cardiac surgical procedures, which should be considered with great concern. Whether ECMO should be used postoperatively in IAAD patients is still a controversial subject, due to some fatal complications linked with it.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758168PMC
http://dx.doi.org/10.1097/MD.0000000000009206DOI Listing

Publication Analysis

Top Keywords

coronary artery
12
iatrogenic acute
8
acute aortic
8
aortic dissection
8
off-pump coronary
8
artery bypass
8
bypass grifting
8
surgery
5
dissection induced
4
induced off-pump
4

Similar Publications

Right ventricular myocardial infarction (RVMI) is a significant and distinct form of acute myocardial infarction associated with considerable morbidity and mortality. It occurs most commonly due to proximal right coronary artery obstruction, often in conjunction with inferior myocardial infarction. RVMI poses unique diagnostic and therapeutic challenges due to the anatomical and functional differences between the right and left ventricles.

View Article and Find Full Text PDF

Interleukin-34 (IL-34) was recently reported to be a new biomarker for atherosclerosis diseases, such as coronary artery disease and vascular dementia. IL-34 regulates the expression of proinflammatory cytokines (IL-17A, IL-1 and IL-6), which are classical cytokines involved in myocardial ischemia‒reperfusion (MI/R) injury. However, the exact role of IL-34 in MI/R remains unknown.

View Article and Find Full Text PDF

Video-based estimation of blood pressure.

PLoS One

January 2025

Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, United States of America.

In this work, we propose a non-contact video-based approach that estimates an individual's blood pressure. The estimation of blood pressure is critical for monitoring hypertension and cardiovascular diseases such as coronary artery disease or stroke. Estimation of blood pressure is typically achieved using contact-based devices which apply pressure on the arm through a cuff.

View Article and Find Full Text PDF

This study aims to evaluate the implementation of concomitant CAD assessment on pre-TAVI (transcatheter aortic valve implantation) planning CTA (CT angiography) aided by CT-FFR (CT-fractional flow reserve) [The CT2TAVI protocol] and investigates the incremental value of CT-FFR to coronary CT angiography (CCTA) alone in the evaluation of patients undergoing CT2TAVI. This is a prospective observational real-world cohort study at an academic health system on consecutive patients who underwent CTA for TAVI planning from 1/2021 to 6/2022. This represented a transition period in our health system, from not formally reporting CAD on pre-TAVI planning CTA (Group A) to routinely reporting CAD on pre-TAVI CTA (Group B; CT2TAVI protocol).

View Article and Find Full Text PDF

Purpose Of Review: What is the pathophysiology and clinical findings as well as management of patients presenting with INOCA/MINOCA (Ischemia/Myocardial Infarction with Non-Obstructive Coronary Arteries).

Recent Findings: INOCA/MINOCA has a complex pathophysiology. In this review article, we aim to summarize the complex pathophysiology and clinical diagnosis, and review the current management options.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!