Peri-implantitis is a long-term complication that frequently occurs after implant surgery. Several treatment methods have been proposed that are aimed at arresting the disease and potentially regenerating bone defects related to it. The use of a combination of proposed decontaminative treatments could possibly improve outcomes. In this case report the authors describe a combined mixed protocol, in which chemical decontamination and a laser-assisted decontamination technique are used in a surgical regenerative approach to successfully manage and treat a case of peri-implantitis. The combined surgical and antimicrobial protocol described can be a suitable treatment option in cases in which implants show severe bone resorption as a result of peri-implant disease.
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