The Effect of Human-Immunodeficiency Virus Status on Outcomes in Penetrating Abdominal Trauma: An Interim Analysis.

World J Surg

Trauma Center, Department of Surgery, Groote Schuur Hospital, University of Cape Town, Observatory, Cape Town, 7925, South Africa.

Published: August 2018

AI Article Synopsis

  • The study examined whether HIV status affects outcomes in hemodynamically stable patients undergoing laparotomy for penetrating abdominal trauma.
  • The research included data from 209 patients, showing that 13% were HIV positive, with a low death rate and significant complication rates overall; however, most outcomes were similar regardless of HIV status.
  • Key findings indicated that factors like the penetrating abdominal trauma index (PATI), age, and trauma score influenced complications and ICU admissions, but HIV status did not impact the overall outcomes significantly.

Article Abstract

Background: The purpose of this study was to determine whether the outcomes of hemodynamically stable patients undergoing exploratory laparotomy for penetrating abdominal trauma differed as a result of their HIV status.

Methods: This was an observational, prospective study from February 2016 to May 2017. All hemodynamically stable patients with penetrating abdominal trauma requiring a laparotomy were included. The mechanism of injury, the HIV status, age, the penetrating abdominal trauma index (PATI), and the revised trauma score (RTS) were entered into a binary logistic regression model. Outcome parameters were in-hospital death, morbidity, admission to intensive care unit (ICU), relaparotomy within 30 days, and length of stay longer than 30 days.

Results: A total of 209 patients, 94% male, with a mean age of 29 ± 10 years were analysed. Twenty-eight patients (13%) were HIV positive. The two groups were comparable. Ten (4.8%) laparotomies were negative. There were two (0.96%) deaths, both in the HIV negative group. The complication rate was 34% (n = 72). Twenty-nine patients (14%) were admitted to the ICU. A higher PATI, older age, and a lower RTS were significant risk factors for ICU admission. After 30 days, 12 patients (5.7%) were still in hospital. Twenty-four patients (11%) underwent a second laparotomy. The PATI score was the single independent predictor for complications, relaparotomy, and hospital stay longer than 30 days.

Conclusions: Preliminary results reveal that HIV status does not influence outcomes in patients with penetrating abdominal trauma.

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Source
http://dx.doi.org/10.1007/s00268-018-4502-4DOI Listing

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