AI Article Synopsis
- The study reviews the effectiveness of ultrasound-guided core-needle biopsy (CNB) for diagnosing salivary gland tumors, confirming a very high diagnostic accuracy.
- Over eight years, 409 biopsies were performed with a diagnostic success rate of 98.3%, showing strong sensitivity (98.7%) and specificity (99%) for identifying neoplasms.
- CNB is recommended as the preferred method for detecting salivary gland tumors, as it has a low complication rate and provides reliable results, although normal tissue findings may require a repeat biopsy.
Article Abstract
Objectives: To review the diagnostic accuracy of ultrasound-guided core-needle biopsy (CNB) in the diagnosis of salivary gland tumours (SGT).
Methods: Retrospective, institutional review board approved, analysis of the CNB of SGT performed at our centre in 8 years. We used an automatic 18-G spring-loaded device. The final diagnosis was based on surgery in the cases that were operated on, and on clinical evolution and biopsy findings in the rest.
Results: Four hundred and nine biopsies were performed in 381 patients (ages, 2-97 years; mean, 55.9). There were two minor complications. Biopsy was diagnostic in 98.3%. There were eight false negatives. The diagnostic values for malignancy were: sensitivity 89.6%, specificity 100%, positive predictive value (PPV) 100% and negative predictive value (NPV) 98%. For the detection of neoplasms were: sensitivity 98.7%, specificity 99%, PPV 99.7% and VPN 96.1%.
Conclusions: Accuracy of CNB in SGT is very high, with a very high sensitivity and an absolutely reliable diagnosis of malignancy. Complication rate is very low. It should be considered the technique of choice when a STG is detected. Normal tissue results warrant repeating biopsy.
Key Points: • Ultrasound-guided core-biopsy is the technique of choice in salivary glands nodules • Sensitivity, specificity for detecting neoplasms (which should be resected) are around 99% • Diagnosis of malignancy in core-biopsy is absolutely reliable • A CNB result of "normal tissue", however, warrants repeating the biopsy • Complication rate is very low.
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| http://dx.doi.org/10.1007/s00330-017-5295-9 | DOI Listing |
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