[Cell complexity should be placed at the heart of cancer research].

Med Sci (Paris)

Institut Curie, université de recherche Paris sciences et lettres (PSL), CNRS, UMR 144, 26, rue d'Ulm, 75248 Paris Cedex 05, France.

Published: January 2018

Genetic and most likely epigenetic alterations occurring during tumor progression and metastatic process lead to a broad deregulation of major cellular functions. However, the molecular mechanisms involved are still poorly understood. To understand them, the cell, the basic unit of life, remains more than ever the essential level to integrate the functional impact of genetics and epigenetics processes in the light of the global economy of the normal and cancerous cell, and of its interactions with its microenvironment.

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Source
http://dx.doi.org/10.1051/medsci/20183401015DOI Listing

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