Background: We report an unusual case of a synchronous rectal and metachronous vaginal metastatic renal cell carcinoma.

Case Presentation: A 78-year-old woman presented with hematochezia and a colonoscopy revealed a metastatic clear-cell renal cell carcinoma rectal polyp biopsy-proven. Abdominal computed tomography identified a 9.0-cm left renal mass with renal vein thrombosis, for which she underwent a laparoscopic radical nephrectomy. Histopathological examination confirmed a pT clear-cell renal cell carcinoma. Seven months later, the patient presented with vaginal bleeding. Physical examination revealed a vaginal polypoid mass and biopsy confirmed a clear-cell renal cell carcinoma metastasis.

Conclusions: This case represents unusual manifestations of metastatic renal cell carcinoma and is a reminder of the wide spectrum of clinical course of this disease.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791369PMC
http://dx.doi.org/10.1186/s12894-018-0317-8DOI Listing

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