Western lifestyle and immunopathology of multiple sclerosis.

Ann N Y Acad Sci

VIB Laboratory of Translational Immunomodulation, Center for Inflammation Research, Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium.

Published: April 2018

There is increasing evidence for a sudden and unprecedented rise in the incidence of multiple sclerosis (MS) in Westernized countries over the past decades, emphasizing the role of environmental factors. Among many candidates, rapid changes in dietary habits seem to play a role in the pathogenesis of MS. Here, we summarize and discuss the available evidence for the role of dietary nutrients, such as table salt, fatty acids, and flavonoids, in the development and pathogenesis of MS. We also discuss new and emerging risk factors accompanying Western lifestyle, such as shift work, sleep, and circadian disruption.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947729PMC
http://dx.doi.org/10.1111/nyas.13583DOI Listing

Publication Analysis

Top Keywords

western lifestyle
8
multiple sclerosis
8
lifestyle immunopathology
4
immunopathology multiple
4
sclerosis increasing
4
increasing evidence
4
evidence sudden
4
sudden unprecedented
4
unprecedented rise
4
rise incidence
4

Similar Publications

Sedentary lifestyles and prolonged physical inactivity are often linked to poor mental and physical health as well as an increased risk of a number of chronic illnesses, including cancer, obesity, type 2 diabetes, and cardiovascular problems. Metabolic Syndrome (MetS), as the new disease, has emerged as the world's leading cause of illness. Despite having its roots in the West, this issue has now completely globalized due to the development of the Western way of life throughout the world.

View Article and Find Full Text PDF

Unraveling the landscape of pediatric pancreatic tumors: Insights from Japan.

World J Gastrointest Oncol

January 2025

Faculty of Medicine, Imperial College London, London SW7 2AZ, United Kingdom.

Pediatric pancreatic tumors, though rare, pose significant diagnostic and management challenges. The recent, 22-year nationwide survey on pediatric pancreatic tumors in Japan by Makita offers valuable insights into this uncommon entity, revealing striking geographical variations and questioning current treatment paradigms. This editorial commentary analyzes the study's key findings, including the predominance of solid pseudopapillary neoplasms and their younger age of onset, which contrast sharply with Western data.

View Article and Find Full Text PDF

Introduction: Individuals with hearing loss and hearing aid users report higher levels of listening effort and fatigue in daily life compared with those with normal hearing. However, there is a lack of objective measures to evaluate these experiences in real-world settings. Recent studies have found that higher sound pressure levels (SPL) and lower signal-to-noise ratios (SNR) are linked to increased heart rate and decreased heart rate variability, reflecting the greater effort required to process auditory information.

View Article and Find Full Text PDF

Ramadan intermittent fasting for patients with gastrointestinal and hepatobiliary diseases: practical guidance for health-care professionals.

Lancet Gastroenterol Hepatol

February 2025

Digestive Diseases Unit, Kettering General Hospital, University Hospital of Northamptonshire NHS Group, Kettering, UK; Department of Population Health Sciences, College of Life Sciences, University of Leicester, Leicester, UK.

Ramadan intermittent fasting can pose challenges and risks for some groups of patients. Based on a narrative literature review and our clinical expertise, we provide practical guidance for clinicians managing patients with gastrointestinal and hepatobiliary conditions who wish to fast during Ramadan. Following the established International Diabetes Federation and Diabetes and Ramadan International Alliance risk stratification framework, we categorised patients' risk as low or moderate, high, or very high.

View Article and Find Full Text PDF

Understanding influences on psychiatry specialty selection in Victoria's Medical workforce.

Australas Psychiatry

January 2025

Alfred Mental and Addiction Health, Melbourne, VIC, Australia.

Objective: Australia faces a psychiatrist shortage, making it crucial to understand factors influencing specialty choice and workforce retention.

Method: An online cross-sectional survey was conducted among medical doctors in their prevocational and vocational stages working in Victoria, Australia. Participants were asked about various factors that influenced their choice of specialty.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!