Background: Subcutaneous fat necrosis (SCFN) is a rare, self-limiting condition that has been associated with several complications including hypercalcemia.

Case Presentation: We present the case of a 6-week-old male who presented to his pediatrician with a dime-sized erythematous nodule consistent with SCFN, who was also found to have supraventricular tachycardia (SVT). Laboratory findings revealed hypercalcemia and hyperkalemia. Extensive evaluation for the electrolyte disturbances revealed no other etiology. This case reinforces that SCFN should be considered in newborns with hypercalcemia of unknown etiology. Additionally, this case is the first to suggest a connection between SCFN and hyperkalemia. Electrolyte abnormalities can potentially contribute to arrhythmogenesis and may have triggered the arrhythmia in our patient.

Conclusions: Our case highlights the importance of remaining vigilant in the workup of atypical rashes of the infant, which should include early assessment of serum electrolytes.

Download full-text PDF

Source
http://dx.doi.org/10.1515/jpem-2017-0365DOI Listing

Publication Analysis

Top Keywords

hypercalcemia hyperkalemia
8
supraventricular tachycardia
8
subcutaneous fat
8
fat necrosis
8
hyperkalemia supraventricular
4
tachycardia patient
4
patient subcutaneous
4
necrosis background
4
background subcutaneous
4
scfn
4

Similar Publications

Diuretics in patients with chronic kidney disease.

Nat Rev Nephrol

January 2025

AHEPA Hospital, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Diuretic drugs act on electrolyte transporters in the kidney to induce diuresis and are often used in chronic kidney disease (CKD), given that nephron loss creates a deficit in the ability to excrete dietary sodium, which promotes an increase in plasma volume. This rise in plasma volume is exacerbated by CKD-induced systemic and intra-renal activation of the renin-angiotensin-aldosterone-system, which further limits urinary sodium excretion. In the absence of a compensatory decrease in systemic vascular resistance, increases in plasma volume induced by sodium retention can manifest as a rise in systemic arterial blood pressure.

View Article and Find Full Text PDF

Impact of adolescents' binge drinking on blood chemistry.

Eur J Pediatr

December 2024

Pediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Della Commenda 9, 20122, Milan, Italy.

Article Synopsis
  • - The study examined the effects of binge drinking on adolescent blood chemistry, focusing on glucose, sodium, calcium, potassium, and acid-base balance, by analyzing medical records from 173 teenagers treated at a Milan hospital between 2013 and 2023.
  • - Results showed that while glucose, sodium, and calcium levels were generally stable, there were significant cases of hypokalemia and an overwhelming presence of acute respiratory acidosis among binge drinkers.
  • - The findings indicate that binge drinking in adolescents leads to notable disturbances in acid-base balance and potassium levels, but has little impact on glucose, sodium, and calcium levels.
View Article and Find Full Text PDF
Article Synopsis
  • Hypoadrenocorticism in cats is rare, often presenting with abnormal serum sodium and potassium levels, but some cases show normal values; a study analyzed 41 cats with varying results.* -
  • The study found that cats with electrolyte imbalances were more likely to exhibit symptoms like hypothermia and weakness, while over half of the subjects (85.4%) were discharged after treatment.* -
  • About one-third of the cats showed hypercalcemia, and those without serious underlying conditions often had a good prognosis post-hospitalization; testing for exocrine pancreatic insufficiency is recommended.*
View Article and Find Full Text PDF

Electrolyte and Acid-Base Abnormalities After Kidney Transplantation.

Adv Kidney Dis Health

September 2024

Renal-Electrolyte and Hypertension Division, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.

Article Synopsis
  • Kidney transplantation is the best treatment for end-stage kidney disease, with 25,500 new transplants recorded in the U.S. in 2022.
  • After transplantation, patients often face various electrolyte imbalances like low magnesium and high potassium, which differ from those in chronic kidney disease.
  • The article focuses on the causes of these imbalances, including the functioning of the transplanted kidney, the effects of immunosuppressive drugs, and metabolic changes post-surgery.
View Article and Find Full Text PDF

Electrolyte disorders related emergencies in children.

BMC Nephrol

August 2024

Department of Pediatric Nephrology, Akron Children's Hospital, Cleveland, OH, USA.

Article Synopsis
  • The article reviews electrolyte and water balance in children, highlighting common electrolyte problems faced in medical settings.
  • It emphasizes the importance of understanding the underlying causes, taking thorough patient histories, conducting physical exams, and using lab tests for effective management.
  • The goal is to improve the handling of emergencies related to electrolyte imbalances in pediatric patients, thereby enhancing their overall health outcomes.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!