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Ruminal-buccal microbiota transmission and their diagnostic roles in subacute rumen acidosis in dairy goats.
J Anim Sci Biotechnol
March 2025
College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
Background: Subacute rumen acidosis (SARA) is a common metabolic disorder in ruminants that disrupts the rumen microbiome and animal health, but diagnosis is challenging due to subtle symptoms and invasive testing requirements. This study explores the potential of the buccal (oral) microbiome as a diagnostic indicator for SARA, hypothesizing an interaction with the rumen microbiome.
Results: The study involved 47 dairy goats, including 11 on a control diet and 36 on high-concentrate diets with increasing rumen-degradable starch.
The effect of diagnostic hypercapnic cerebrovascular reactivity imaging on vital signs and acute and follow-up ischemic adverse events in patients with flow-limiting intracranial arterial stenosis.
AJNR Am J Neuroradiol
February 2025
From the Department of Neurology (M.L., C.H., M.H., W.T.R., L.T.D., L.C.J., M.J.D.), Department of Radiology and Radiological Sciences (L.T.D., M.F., R.C., L.C.J.), Department of Neurosurgery (M.F., R.C.), Department of Pediatrics (L.C.J.), and Department of Psychiatry and Behavioral Sciences (M.J.D.), Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Background And Purpose: Anatomical imaging is a hallmark for visualizing chronic and acute infarcts but provides incomplete information on stroke risk. Respiratory hypercapnic gas challenges show promise for non-invasively assessing hemodynamic function and mapping cerebrovascular reserve capacity, an indicator of how near parenchyma is to exhausting autoregulatory capacity. However, limited safety information exists for this method in high-risk patients with flow-limiting stenosis.
View Article and Find Full Text PDFSinusitis.
Prim Care
March 2025
Department of Family Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
This study provides a comprehensive overview of sinusitis, detailing its pathophysiology, clinical manifestations, diagnostic criteria, and management strategies. Sinusitis, characterized by inflammation of the paranasal sinuses, can be acute, subacute, recurrent, or chronic, with distinct clinical presentations and treatment approaches. Diagnosis relies on clinical evaluation, imaging studies, and occasionally nasal endoscopy.
View Article and Find Full Text PDFAtheroembolic Kidney Disease and Atypical Hemolytic Uremic Syndrome: Two Sides of the Same Coin?
Kidney Blood Press Res
March 2025
Department of Public Health, Chair of Nephrology, University of Naples "Federico II", Naples, Italy.
Introduction: Atheroembolic kidney disease (AEKD) is an under-recognized cause of kidney failure, secondary to the obstruction of the renal artery and/or its branches due to the rupture of an unstable atherosclerotic plaque in patients treated with surgical and invasive cardiovascular procedures. The embolization of cholesterol crystals in the renal artery activates the complement and triggers an inflammatory reaction. Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy caused by the hyperactivation of the alternative complement pathway, leading to a prothrombotic and proinflammatory state on the endothelial surface.
View Article and Find Full Text PDFSuccessful treatment of rapid onset Foix-Alajouanine syndrome following hyperselective endovascular embolization of thoracic dural arteriovenous fistula: Case report, technical note and literature review.
J Cerebrovasc Endovasc Neurosurg
February 2025
Department of Neuroendovascular, National Institute of Neurology and Neurosurgery, Mexico.
Foix-Alajouanine syndrome is an extremely rare yet important differential diagnosis for subacute lower limb weakness in middle-aged to elderly adults. Current understanding of the pathophysiology of this disease, along with recent publications on successful endovascular interventions, has shifted the perspective and clinical approach for its management. Nonetheless, neurosurgical pathways for clinical treatment are still preferred over endovascular embolization.
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