Asymmetric cascade double Michael additions to construct 2'-substituted 3,3'-spirooxindoles by using a chiral guanidine organocatalyst has been developed. A series of spirooxindole derivatives containing dihydrofuran or pyrrolidine subunits were obtained with good to excellent diastereo- and enantioselectivities. The method showed great tolerance of a number of aromatic and aliphatic alkynones. The strategy gave access to the asymmetric synthesis of (-)-salacin for the first time.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/chem.201800043 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
No distinct local cuisines among humpback whales: A population diet comparison in the Southern Hemisphere.
Sci Total Environ
June 2024
Centre for Planetary Health and Food Security, Southern Ocean Persistent Organic Pollutants Program, Griffith University, 4111 Nathan, QLD, Australia.
Southern hemisphere humpback whale (Megaptera novaeangliae, SHHW) breeding populations follow a high-fidelity Antarctic krill (Euphausia superba) diet while feeding in distinct sectors of the Southern Ocean. Their capital breeding life history requires predictable ecosystem productivity to fuel migration and migration-related behaviours. It is therefore postulated that populations feeding in areas subject to the strongest climate change impacts are more likely to show the first signs of a departure from a high-fidelity krill diet.
View Article and Find Full Text PDFAustralia's east coast humpback whales: Satellite tag-derived movements on breeding grounds, feeding grounds and along the northern and southern migration.
Biodivers Data J
December 2023
Australian Antarctic Division, Department of Climate Change, Energy, the Environment and Water, Hobart, Australia Australian Antarctic Division, Department of Climate Change, Energy, the Environment and Water Hobart Australia.
Background: Satellite tags were deployed on 50 east Australian humpback whales (breeding stock E1) between 2008 and 2010 on their southward migration, northward migration and feeding grounds in order to identify and describe migratory pathways, feeding grounds and possible calving areas. At the time, these movements were not well understood and calving grounds were not clearly identified. To the best of our knowledge, this dataset details all long-term, implantable tag deployments that have occurred to date on breeding stock E1.
View Article and Find Full Text PDFRed-list status and extinction risk of the world's whales, dolphins, and porpoises.
Conserv Biol
October 2023
IUCN Species Survival Commission, Cetacean Specialist Group.
To understand the scope and scale of the loss of biodiversity, tools are required that can be applied in a standardized manner to all species globally, spanning realms from land to the open ocean. We used data from the International Union for the Conservation of Nature Red List to provide a synthesis of the conservation status and extinction risk of cetaceans. One in 4 cetacean species (26% of 92 species) was threatened with extinction (i.
View Article and Find Full Text PDFSatellite tag derived data from two Antarctic blue whales () tagged in the east Antarctic sector of the Southern Ocean.
Biodivers Data J
December 2022
Australian Antarctic Division, Kingston, Australia Australian Antarctic Division Kingston Australia.
Background: Satellite tags were deployed on two Antarctic blue whales () in the east Antarctic sector of the Southern Ocean as part of the International Whaling Commission's Southern Ocean Research Partnership initiative. The satellite tracks generated are the first and currently, the only, satellite telemetry data that exist for this critically endangered species. These data provide valuable insights into the movements of Antarctic blue whales on their Antarctic feeding ground.
View Article and Find Full Text PDFhiphop: Improved paternity assignment among close relatives using a simple exclusion method for biallelic markers.
Mol Ecol Resour
August 2021
Division of Ecology and Evolution, Research School of Biology, The Australian National University, Canberra, ACT, Australia.
Assignment of parentage with molecular markers is most difficult when the true parents have close relatives in the adult population. Here, we present an efficient solution to that problem by extending simple exclusion approaches to parentage analysis with single nucleotide polymorphic markers (SNPs). We augmented the previously published homozygote opposite test (hot), which counts mismatches due to the offspring and candidate parent having different homozygous genotypes, with an additional test.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!