The diagnostic spectrum for scalp lesions is extensive and comprises either benign or malignant features. Cornu cutaneum (CC) is a well-recognized condition; however, its origin and natural course are not always obvious. We present the case of a 78-year-old male patient who was diagnosed with intracranial meningioma in 2014 and who subsequently refused treatment. He presented a new scalp lesion, resembling a horn, in the vertex region 1.5 years after his last follow-up. The lesion was excised, and the patient was histopathologically diagnosed as having CC caused by squamous cell carcinoma. CC can be easily recognized when it resembles animal horn; however, it can assume different shapes that require a physician to be vigilant. Moreover, a lesion’s benign or malignant nature is not obvious in all cases. Hard, protruding scalp lesions should be examined for CC, and a histopathological evaluation should be performed to make a definitive diagnosis.

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http://dx.doi.org/10.5137/1019-5149.JTN.22091-17.1DOI Listing

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Article Synopsis
  • A cutaneous horn, or cornu cutaneum, is a growth made of keratinizing skin cells that often develops over underlying skin lesions such as benign and malignant tumors, infections, or other skin conditions.
  • The text describes two cases: a 22-year-old woman with a cutaneous horn linked to a stubborn wart on her toe, and a 57-year-old man with a horn associated with inverted follicular keratosis on his lip.
  • The most common conditions related to cutaneous horns are actinic keratosis, squamous cell carcinoma, and seborrheic keratosis, with several benign and malignant tumors associated with these skin growths.
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Giant Cutaneous Horn (Cornu Cutaneum) Developing from a Hypertrophic Burn Scar.

Adv Skin Wound Care

February 2022

Nur Cihan Cosansu, MD, is Dermatologist, Sakarya University, Education and Research Hospital, Department of Dermatology, Sakarya, Turkey. Tuba Cetiner, MD, is Dermatologist, Izmit Seka State Hospital, Department of Dermatology, Kocaeli, Turkey. Gülcan Yuksekal, MD, is Dermatologist, Yenikent State Hospital, Department of Dermatology, Sakarya, Turkey. The authors have disclosed no financial relationships related to this article. Submitted January 2, 2021; accepted in revised form March 12, 2021.

A cornu cutaneum (CC) is a rare lesion. This case report describes a 63-year-old woman with a giant CC lesion on her right hip arising from a hypertrophic burn scar at its base. To the authors' knowledge, this is the first case described in the literature of a CC that developed from a burn scar.

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A cutaneous horn, sometimes referred to as cornu cutaneum, is a projection arising on the skin due to an overgrowth of the epidermal stratum corneum. This lesion is a clinical presentation of an underlying skin tumor. A woman with a verruca vulgaris-associated cutaneous horn is described.

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