Inhibiting contact activation of factor XI during reperfusion of acute myocardial ischemia reduces infarct size in mice. Factor XII/XI contact axis inhibition may improve the outcome of coronary artery recanalization in acute myocardial infarction.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787867PMC
http://dx.doi.org/10.1182/bloodadvances.2017004879DOI Listing

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