Purpose: To assess the image quality, scatter, and leakage radiation of an integrated magnetic resonance linear accelerator (MR-LINAC or MRL) system.
Methods: A large American College of Radiology (ACR) magnetic resonance imaging (MRI) accreditation phantom was used to evaluate the MRI capabilities of the integrated MRL system compared with those of other diagnostic MRI systems. Multiple sets of T1 and T2/PD images were acquired with the linear accelerator positioned at various angles and with the radiation beam on and off. Images also were acquired on three different occasions over a period of about 12 months. Scatter and leakage radiation were measured with a large (150 cm ) ion chamber recalibrated for MV energy. For scatter measurements, a 25-cm stack of solid-water materials was placed at the isocenter on the patient couch to simulate a patient. The head leakage was measured at 1 m from the linear accelerator head in directions determined to produce the maximum leakage. All measurements were repeated with the magnetic field turned off to study the effects of the magnetic field.
Results: The geometric distortion, slice thickness accuracy, image uniformity, ghosting ratio, and high-contrast detectability were comparable to other 1.5 T diagnostic MRI scanners. No observable changes in image quality and no appreciable differences were found between radiation beam-on and beam-off images. The measured leakage and scattered radiation changed by less than 5% when the magnetic field was on compared to measurements with the field off. The beam stopper leakage was approximately 0.3 R/1000 MU, and because there was no direct beam imparted on the walls, a vault designed for a modern-day LINAC should have enough required radiation shielding to house the MRL.
Conclusions: The image quality generated by the MRI system of the integrated MRL was similar to that of a diagnostic MRI scanner. Interference from the MV radiation was minimal, and there was no measurable difference in image quality with the beam on and off. Scatter radiation and leakage radiation of the MRL system were within the expected range of a comparable MV-LINAC.
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http://dx.doi.org/10.1002/mp.12767 | DOI Listing |
JAMA Neurol
January 2025
Department of Neurology, UAB Heersink School of Medicine, University of Alabama at Birmingham, Birmingham.
Importance: In the Atrial Cardiopathy and Antithrombotic Drugs in Prevention After Cryptogenic Stroke (ARCADIA) randomized clinical trial, anticoagulation did not prevent recurrent stroke among patients with a recent cryptogenic stroke and atrial cardiopathy. It is unknown whether anticoagulation prevents covert infarcts in this population.
Objective: To test the use of apixaban vs aspirin for prevention of nonlacunar covert infarcts after cryptogenic stroke in patients with atrial cardiopathy.
Curr Rheumatol Rep
January 2025
Rheumatologisches Versorgungszentrum Steglitz, Ruhr Universität Bochum, Schloßstr.110, 12163, Berlin, Germany.
Purpose Of Review: Axial spondyloarthritis (axSpA) is a rather prevalent chronic inflammatory rheumatic disease that affects already relatively young patients. It has been known better since the end of the nineteenth century but quite a lot has been learned since the early 60ies when the first classification (diagnostic) criteria for ankylosing spondylitis (AS) were agreed on. I have been part of many developments in the last 30 years, and I'm happy to have been able to contribute to the scientific progress in terms of diagnosis, imaging, pathophysiology and therapy.
View Article and Find Full Text PDFUnfallchirurgie (Heidelb)
January 2025
Klinik für Orthopädie, Unfallchirurgie und Plastische Chirurgie, Universitätsklinikum Leipzig AöR, Liebigstraße 20, 04103, Leipzig, Deutschland.
Fractures of the thoracic (Th) and lumbar (L) vertebrae are among the most frequent fracture entities in Germany and particularly affect the thoracolumbar junction (TLJ; Th11-L2). Based on expert recommendations and consensus meetings, the thoracolumbar AOSpine injury score was established for patients with healthy bone and the osteoporotic fracture (OF) score for geriatric patients with the respective classifications for treatment decisions. In both cohorts, the treatment decision is based on the fracture morphology, neurological status and patient-specific contextual factors.
View Article and Find Full Text PDFPurpose: The depth within the body, small diameter, long length, and varying tissue surrounding the spinal cord impose specific considerations when designing radiofrequency coils. The optimal coil configuration for 7 T cervical spinal cord MRI is unknown and, currently, there are very few coil options. The purpose of this work was (1) to establish a quality control protocol for evaluating 7 T cervical spinal cord coils and (2) to use that protocol to evaluate the performance of 4 different coil designs.
View Article and Find Full Text PDFInt J Biomed Imaging
January 2025
Medical Imaging Sciences Department, College of Health Sciences, Gulf Medical University, Ajman, UAE.
The quality of CT images obtained from hepatocellular carcinoma (HCC) patients is complex, affecting diagnostic accuracy, precision, and radiation dose assessment due to increased exposure risks. The study evaluated image quality qualitatively and quantitatively by comparing quality levels with an effective radiation dose to ensure acceptable quality accuracy. This study retrospectively reviewed 100 known HCC patients (Li-RADS-5) who underwent multidetector computed tomography (MDCT) multiphasic scans for follow-up of their health condition between January and October 2023.
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