Scarring Airway Stenosis in Chinese Adults: Characteristics and Interventional Bronchoscopy Treatment.

Chin Med J (Engl)

Department of Respiratory, Beijing Tian Tan Hospital, Capital Medical University, Beijing 100050, China.

Published: February 2018

AI Article Synopsis

  • Scarring airway stenosis in China is primarily caused by endotracheobronchial tuberculosis (EBTB), particularly affecting young women and primarily located in the left main bronchus.
  • The study analyzed data from 392 patients and determined that the average length of post-tuberculosis airway scarring was often between 1.1-2.0 cm.
  • Interventional bronchoscopy is found to be a useful and safe treatment, with a clinical success rate of approximately 60.5% among patients.

Article Abstract

Background: Scarring airway stenosis is commonly seen in China as compared to other developed countries, due to the high prevalence of tuberculosis. Nowadays, interventional bronchoscopy treatment has been widely used to treat this disease in China. This study demonstrated the characteristics of scarring airway stenosis in Chinese adults and retrospectively evaluated the efficacy of interventional bronchoscopy treatment of this disease.

Methods: Patients with scarring airway stenosis from 18 tertiary hospitals were enrolled between January 2013 and June 2016. The causes, site, and length of scarring airway stenosis were analyzed, and the efficacy of the interventional bronchoscopy treatment was evaluated.

Results: The final study cohort consisted of 392 patients. Endotracheobronchial tuberculosis (EBTB) was the most common cause of scarring airway stenosis (305/392, 77.8%) in Chinese adults with a high rate of incidence in young women. The left main bronchus was most susceptible to EBTB, and most posttuberculosis airway scarring stenosis length was 1.1-2.0 cm. The average clinical success rate of interventional bronchoscopy treatment for scarring airway stenosis in Chinese patients is 60.5%. The stent was inserted in 8.7% scarring airway stenosis in China.

Conclusions: Scarring airway stenosis exhibits specific characteristics in Chinese patients. Interventional bronchoscopy is a useful and safe treatment method for the disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798047PMC
http://dx.doi.org/10.4103/0366-6999.223850DOI Listing

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