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Down the Digital Rabbit Hole: Objectification Increases Problematic Gaming.
Cyberpsychol Behav Soc Netw
January 2025
Faculty of Psychology, South China Normal University, Guangzhou, China.
Objectification, being perceived and treated merely as an object with a denial of one's humanness, has been linked to numerous adverse outcomes in daily life. Despite this, its influence on online behaviors, particularly problematic gaming, remains underexplored. The current research (total = 1,000) extends the literature on objectification by investigating the effect of objectification on problematic gaming.
View Article and Find Full Text PDFDrinking intention-behavior links vary by affect among heavy-drinking young adults: An ecological momentary assessment and transdermal sensor study.
Psychol Addict Behav
January 2025
Department of Biobehavioral Health, Bennett Pierce Prevention Research Center, Pennsylvania State University.
Objective: Drinking intention is a predictor of heavy-drinking episodes and could serve as a real-time target for preventive interventions. However, the association is inconsistent and relatively weak. Considering the affective context when intentions are formed might improve results by revealing conditions in which intention-behavior links are strongest and the predictive power of intentions is greatest.
View Article and Find Full Text PDFFirst-line pembrolizumab-axitinib versus sunitinib in metastatic RCC: subgroup analysis of patients enrolled in the phase 3 KEYNOTE-426 in Eastern Asia.
Jpn J Clin Oncol
January 2025
Kindai University Hospital, 377-2 Onohigashi, Osakasayama, 589-8511, Osaka, Japan.
Background: The phase 3 open-label KEYNOTE-426 study demonstrated that first-line pembrolizumab plus axitinib improved overall survival (OS) and progression-free survival (PFS) versus sunitinib for metastatic renal cell carcinoma (mRCC) in a global population. This subgroup analysis investigated the efficacy and safety of pembrolizumab-axitinib versus sunitinib in patients enrolled in KEYNOTE-426 in East Asia (Japan, South Korea, and Taiwan).
Methods: Adults with clear cell mRCC were randomly assigned 1:1 to receive intravenous pembrolizumab 200 mg every 3 weeks with oral axitinib 5 mg twice daily or oral sunitinib 50 mg once daily (4 weeks on/2 weeks off).
Metformin for low back pain: Study protocol for a randomised, double-blind, placebo-controlled trial.
Osteoarthr Cartil Open
March 2025
School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, 3004, Australia.
Background: Chronic low back pain is a major cause of pain and disability with limited effective therapies. Metformin is a safe, inexpensive, well-tolerated drug that has pleotropic effects, including effects on pain pathways that may influence low back pain. The aim of this randomised, double-blind, placebo-controlled trial is to determine whether metformin reduces low back pain over 4 months in individuals with chronic low back pain.
View Article and Find Full Text PDFManaging the work of living with heart failure: a qualitative study using the cumulative complexity model from Southeastern Minnesota.
BMJ Open
December 2024
Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA
Objective: Patients with heart failure (HF) perform a variety of self-care activities to control symptoms and minimise the risk of HF decompensations. The objective of this study was to understand how patients build capacity and manage the work of living with HF.
Design: A qualitative study using semi-structured telephone interviews.
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