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Life-threatening autoimmune warm hemolytic anemia following treatment for multiple sclerosis with alemtuzumab. | LitMetric
Background : Alemtuzumab is a humanized monoclonal antibody directed at CD52 approved as a disease-modifying therapy for relapsing forms of multiple sclerosis (MS).Objective : To describe a case of a life-threatening autoimmune anemia occurring after a first course of alemtuzumab for relapsing-remitting MS in a 28-year-old male.Methods : Case report.Results : A 28-year-old male developed a life-threatening autoimmune anemia occurring 11 months after first alemtuzumab course.Conclusion : We report the third case of autoimmune hemolytic anemia following treatment with alemtuzumab in a young MS patient. Due to the severity of this adverse event, neurologists using this treatment should be alert.
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