A Randomized Comparison of Bougie-Assisted and TracheoQuick Plus Cricothyrotomies on a Live Porcine Model.

Biomed Res Int

Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic (AS CR), Rumburska 89, 277 21 Libechov, Czech Republic.

Published: August 2018

Objectives: Cricothyrotomy is a rescue procedure in "cannot intubate, cannot oxygenate" scenarios where other methods of nonsurgical airway management have failed. We compared 2 cuffed cricothyrotomy sets, bougie-assisted cricothyrotomy (BACT) and novel percutaneous TracheoQuick Plus, on a live porcine model in a simulated periarrest situation.

Methods: Thirty-four anesthetized minipigs were randomly allocated into two groups: BACT technique ( = 17) and TracheoQuick Plus ( = 17). The primary outcome was duration of cricothyrotomy while secondary outcomes were total success rate, number of attempts, location of incision, changes in heart rate, oxygen saturation, and the incidence of complications.

Results: BACT was significantly faster than TracheoQuick Plus cricothyrotomy, with a median time of 69 sec (IQR 56-85) versus 178 sec (IQR 152-272). The total success rate was without difference. 94% of BACT was performed successfully on the first attempt, while in the TracheoQuick Plus group, it was only 18% ( < 0.001). Trauma to the posterior tracheal wall was observed once in the BACT group and 5 times in the TracheoQuick Plus group. Oxygen saturation was significantly higher in the BACT group both during and after the procedure.

Conclusions: BACT is superior to TracheoQuick Plus cricothyrotomy on a live animal model.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749220PMC
http://dx.doi.org/10.1155/2017/4215159DOI Listing

Publication Analysis

Top Keywords

live porcine
8
porcine model
8
total success
8
success rate
8
oxygen saturation
8
tracheoquick cricothyrotomy
8
tracheoquick group
8
bact group
8
tracheoquick
7
bact
7

Similar Publications

A newly developed articulated through-the-scope traction device, TRACMOTION, has been used clinically for endoscopic submucosal dissection (ESD). However, there are few reports on the characteristics of this device and the lesion types for which it is most effective. Therefore, we evaluated its optimal use, efficacy, and safety clinically in animals.

View Article and Find Full Text PDF

Comparative analysis of the performance, egg quality and ovarian immune function of fast and slow feather strains in tianfu green shell laying hens at various stages of egg production.

Poult Sci

December 2024

State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, PR China; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu Campus, Chengdu 611130, PR China; Key Laboratory of Livestock and Poultry Multi-omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, PR China. Electronic address:

This objective of this experiment was to compare and evaluate the performance, egg quality, and immune function of Tianfu green shell laying hens with varying feather growth rates, in order to provide a reference for their rational utilization. A total of 120 one-day-old healthy Tianfu green shell laying hens were classified into the early-feathering (EF) and late-feathering (LF) groups through phenotypic identification of feather length and qPCR molecular identification. Each group was subdivided into four replicates, with 30 chickens in each replicate.

View Article and Find Full Text PDF

Traditional Chinese medicine has unique advantages in preventing and treating COVID-19, and Fuzheng Jiedu decoction (FZJDD) was reported to be effective against COVID-19 in clinical trials. To investigate the potential mechanisms and material basis of FZJDD against SARS-CoV-2, we performed SARS-CoV-2 target protein inhibition analyses and a metabolite full spectrum analysis of FZJDD. Interestingly, FZJDD was found to block the binding of SARS-CoV-2 Spike protein with the receptor ACE2 and inhibit the activity of SARS-CoV-2 3CLpro.

View Article and Find Full Text PDF

First case of Streptococcus suis bacteremia caused by a serotype 14 strain without pig or pork contact in the Netherlands: A case report.

Diagn Microbiol Infect Dis

December 2024

Amsterdam UMC location University of Amsterdam, Department of Global Health, Amsterdam Institute for Global Health and Development, Paasheuvelweg 25, Amsterdam, the Netherlands; Amsterdam UMC location University of Amsterdam, Department of Medical Microbiology and Infection Prevention, Meibergdreef 9, Amsterdam, the Netherlands.

Streptococcus suis is a porcine pathogen that causes severe zoonotic infections in humans resulting in meningitis and sepsis. The main risk factors for S. suis zoonotic infections are consumption of raw pork products and direct contact with live pigs or pork, in particular in the presence of skin injuries.

View Article and Find Full Text PDF

Optimizing encephalomyocarditis virus VP1 protein assembly on pseudorabies virus envelope via US9 protein anchoring.

Virulence

December 2025

The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China.

Live herpesvirus-vectored vaccines are critical in veterinary medicine, but they can sometimes offer insufficient protection due to suboptimal antigen expression or localization. Encephalomyocarditis virus (EMCV) is a significant zoonotic threat, with VP1 protein as a key immunogen on its capsid. To enhance immunogenicity, we explored the use of recombinant pseudorabies virus (rPRV) as a vaccine vector against EMCV.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!