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| http://dx.doi.org/10.1161/JAHA.117.008261 | DOI Listing |
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Impact of workflow times on successful reperfusion after endovascular treatment in the late time window.
Neuroradiol J
January 2025
Calgary Stroke Program, Department of Clinical Neurosciences and Radiology, University of Calgary, Canada.
Background And Purpose: Successful and complete reperfusion should be the aim of every endovascular thrombectomy (EVT) procedure. However, the effect of time delays on successful reperfusion in late window stroke patients presenting 6-to-24 h from onset has not been investigated.
Materials And Methods: We pooled individual patient-level data from seven trials and registries for anterior circulation stroke patients treated with EVT between 6 and 24 h from onset.
Circle of Willis Variants and Their Association with Outcome after Successful Revascularization of Anterior Large Vessel Occlusion.
AJNR Am J Neuroradiol
January 2025
Department of Radiology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Background And Purpose: Leptomeningeal collaterals have been associated with better outcomes in large-vessel stroke, but little is known about how the Circle of Willis (CoW) collaterals affect stroke outcomes. We aimed to determine the relationship between three anatomically distinct CoW subtypes and 90-day outcomes in acute ischemic stroke patients after successful revascularization via endovascular thrombectomy (EVT).
Materials And Methods: We performed a retrospective analysis of patients treated with successful EVT for large-vessel occlusion at a comprehensive stroke center between May 2016 and November 2023.
Background: Belzutifan, a first-in-class HIF-2α inhibitor, has shown antitumour activity as monotherapy and in combination with cabozantinib in patients with previously treated advanced kidney cancer. The phase 2 LITESPARK-003 study was designed to determine the antitumour activity and safety of belzutifan in combination with cabozantinib in patients with advanced clear-cell renal cell carcinoma that was previously untreated (cohort 1) or previously treated with immunotherapy (cohort 2). Here, we report results from cohort 1 of this clinical trial.
View Article and Find Full Text PDFExperimental Study of Sawdust Syngas Gasification in Bench-Scale Gasifier and Three-Dimensional Numerical Analysis for Syngas Cocombustion in a 600 MW Coal-Fired Boiler Furnace.
ACS Omega
December 2024
Guangdong Provincial Key Laboratory of Distributed Energy System, Dongguan University of Technology, Dongguan 523820, China.
To comprehensively explore syngas cocombustion technology, gasification experiments in a bench-scale circulating fluidized bed (CFB) and three-dimensional (3D) numerical simulations of a coal-fired boiler furnace have been conducted. In the amplification experiment of biomass gasification, sawdust has been gasified using air, oxygen-enriched air, and steam. The highest heating value of the syngas products reaches 12.
View Article and Find Full Text PDFAssociation Between CT With Angiography and 30-Day Risk of Stroke or Transient Ischemic Attack in a Canadian Emergency Department Setting.
Cureus
November 2024
Emergency Medicine, University of Calgary, Calgary, CAN.
Introduction: A subset of undifferentiated vertigo cases can be attributed to dangerous central causes such as posterior circulation ischemic stroke (PCIS) or transient ischemic attack (TIA). Due to a lack of validated clinical risk scoring tools, there is currently high heterogeneity in emergency department (ED) neuroimaging practices for patients presenting with undifferentiated vertigo. Therefore, this study assessed the utility of head and neck CT with angiography (CTA) for risk stratifying ED patients presenting with vertigo.
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