A luminescent bimetallic iridium(iii) complex for ratiometric tracking intracellular viscosity.

Chem Commun (Camb)

State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, No. 2 linggong Road, Ganjingzi, District, Dalian 116023, China.

Published: February 2018

A luminescent bimetallic iridium probe C10 was developed through a long soft carbon chain linkage to achieve ratiometric detection of viscosity. C10 features high sensitivity and selectivity for viscosity. More importantly, C10 is living cell permeable and can be employed to distinguish cancer cells from normal cells and track viscosity changes during MCF-7 cell apoptosis.

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Source
http://dx.doi.org/10.1039/c7cc09723aDOI Listing

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