Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/ijd.13831 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Fabrication of Thymoquinone and Ascorbic Acid-Loaded Spanlastics Gel for Hyperpigmentation: In Vitro Release, Cytotoxicity, and Skin Permeation Studies.
Pharmaceutics
January 2025
Department of Pharmacy, Faculty of Pharmacy, Zarqa University, Zarqa 13110, Jordan.
: The demand for a safe compound for hyperpigmentation is continuously increasing. Bioactive compounds such as thymoquinone (TQ) and ascorbic acid (AA) induce inhibition of melanogenesis with a high safety profile. The aim of this study was to design and evaluate spanlastics gel loaded with bioactive agents, TQ and AA, for the management of hyperpigmentation.
View Article and Find Full Text PDFUnveiling the Phytochemical Diversity and Bioactivity of : A First Report Integrating Experimental and In Silico Approaches.
Pharmaceuticals (Basel)
January 2025
Department of Molecular Biology and Genetics, Faculty of Science, Kilis 7 Aralik University, 79000 Kilis, Türkiye.
: The genus is renowned for its diverse bioactive potential, yet the chemical composition and biological properties of remain inadequately explored. This study aimed to investigate the chemical profile, antioxidant capacity, and enzyme inhibitory activities of methanol extracts from various plant parts of . : Methanol extracts were obtained from leaves, stems, flowers, roots, and aerial portions of .
View Article and Find Full Text PDFDesign, Synthesis, and Antioxidant and Anti-Tyrosinase Activities of ()-5-Benzylidene-2-(naphthalen-1-ylamino)thiazol-4(5)-one Analogs: In Vitro and In Vivo Insights.
Molecules
January 2025
Department of Manufacturing Pharmacy, College of Pharmacy and Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.
Fifteen compounds (-) constructed on a hybrid structure combining a β-phenyl-α,β-unsaturated carbonyl template and a 2-aminothiazol-4(5)-one scaffold were designed and synthesized as potential novel anti-tyrosinase substances. Two compounds ( and ) showed more potent inhibition against mushroom tyrosinase than kojic acid, and the inhibitory activity of (IC value: 1.60 μM) was 11 times stronger than that of kojic acid.
View Article and Find Full Text PDFIonized Plasma Jet Therapy in Removal of Dermatosis Papulosa Nigra.
Indian Dermatol Online J
December 2024
Department of Dermatology, Venereology and Leprosy, N.K.P. Salve Institute of Medical Sciences and Research Centre and Lata Mangeshkar Hospital, Nagpur, Maharashtra, India.
Background: Dermatosis papulosa nigra (DPN) presents as benign skin growths, predominantly affecting women and often commencing during adolescence. Treatment is sought due to its cosmetic impact, with available modalities often posing risks of scarring and pigmentary changes.
Materials & Methods: This study investigates the efficacy of ionized plasma jet therapy (IPJT) in ten DPN patients at a tertiary care hospital in central India.
Establishing the Cut-Off Values of 17-Hydroxyprogesterone for Diagnosing Congenital Adrenal Hyperplasia: A Prospective Observational Study in a Tertiary Care Hospital.
Cureus
December 2024
Central Research Service, Bharati Vidyapeeth (Deemed to be University) Medical College, Pune, IND.
Introduction Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder primarily caused by 21-hydroxylase enzyme deficiency, impairing cortisol synthesis and resulting in elevated androgen levels. CAH presents in two classical forms: salt-wasting (SW) and simple virilizing (SV). Although CAH is rare in India, regional variations and the absence of a national newborn screening (NBS) program pose significant challenges to accurate diagnosis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!