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Surgical management of single-level thoracolumbar vertebral body segmentation and formation failure causing progressive thoracolumbar myelopathy in three adult large-breed dogs.
Front Vet Sci
January 2025
Lumbry Park Veterinary Specialists, Hampshire, United Kingdom.
Objective: This study aimed to evaluate the medium-term outcome following spinal cord decompression and instrumented fixation of single-level congenital thoracolumbar vertebral malformations, characterized by combined failures of segmentation and formation, causing thoracolumbar myelopathy in three large-breed dogs.
Study Design: This was a retrospective clinical study.
Animals: The animals involved in the study were three large-breed dogs.
Volition as a modulator of the intergroup empathy bias.
Soc Neurosci
January 2025
Center for Research in Cognition and Neuroscience, Université libre de Bruxelles, Brussels, Belgium.
Neural reactions to others' pain are usually lower when the individual is of a different ethnicity than when they are of the same ethnicity. This suggests that empathy is not only an automatic phenomenon but also a motivated one. In the present study, we tested whether one's willingness to increase or decrease empathy would correspondingly increase or decrease the neural empathic response, as measured with electroencephalography (EEG), irrespective of ethnicity.
View Article and Find Full Text PDFNaringenin Suppresses the Hyperexcitability of Trigeminal Nociceptive Neurons Associated with Inflammatory Hyperalgesia: Replacement of NSAIDs with Phytochemicals.
Nutrients
November 2024
Laboratory of Food and Physiological Sciences, Department of Life and Food Sciences, School of Life and Environmental Sciences, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara 252-5201, Kanagawa, Japan.
Article Synopsis
- The study investigates the effects of naringenin (NRG) on inflammation-related hyperexcitability in the spinal trigeminal nucleus caudalis (SpVc), comparing its efficacy to diclofenac (DIC).
- Rats with induced inflammation in their whisker pads showed decreased pain thresholds, which normalized two days after treatment with NRG, DIC, or a combination of both.
- The results revealed that NRG, DIC, and the combined treatment significantly reduced the activity of SpVc neurons and their heightened sensitivity to mechanical stimuli in inflamed rats, suggesting NRG's potential for alleviating inflammatory pain.
Automated acute pain prediction in domestic goats using deep learning-based models on video-recordings.
Sci Rep
November 2024
Department of Clinical Studies - New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Facial expressions are essential in animal communication, and facial expression-based pain scales have been developed for different species. Automated pain recognition offers a valid alternative to manual annotation with growing evidence across species. This study applied machine learning (ML) methods, using a pre-trained VGG-16 base and a Support Vector Machine classifier to automate pain recognition in caprine patients in hospital settings, evaluating different frame extraction rates and validation techniques.
View Article and Find Full Text PDFQualitative somatosensory evaluation of recipient and donor sites of subepithelial connective tissue grafts: a preliminary study.
Clin Oral Investig
September 2024
Department of Periodontics- Bauru School of Dentistry, University of Sao Paulo, Dr. Octávio Pinheiro Brisolla 9-75, Vila Universitária, Bauru, SP, CEP: 17012-901, Brazil.
Objectives: The subepithelial connective tissue graft (SCTG) plus coronal advanced flap is commonly evaluated by clinical parameters, but potential sensory changes (patients' perception of painful or painless sensations) need to be further explored. This preliminary study aimed to qualitatively evaluate the somatosensory profile of recipient and palatal donor sites of SCTG.
Materials And Methods: Sensory tests were applied at SCTG recipient and donor sites at baseline, after 3 and 6 months.
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