Quantification of the anatomic and functional aspects of the tongue is pertinent to analyse the mechanisms involved in speech production. Speech requires dynamic and complex articulation of the vocal tract organs, and the tongue is one of the main articulators during speech production. Magnetic resonance imaging has been widely used in speech-related studies. Moreover, the segmentation of such images of speech organs is required to extract reliable statistical data. However, standard solutions to analyse a large set of articulatory images have not yet been established. Therefore, this article presents an approach to segment the tongue in two-dimensional magnetic resonance images and statistically model the segmented tongue shapes. The proposed approach assesses the articulator morphology based on an active shape model, which captures the shape variability of the tongue during speech production. To validate this new approach, a dataset of mid-sagittal magnetic resonance images acquired from four subjects was used, and key aspects of the shape of the tongue during the vocal production of relevant European Portuguese vowels were evaluated.
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http://dx.doi.org/10.1177/0954411917751000 | DOI Listing |
Crit Care
January 2025
Department of Critical Care Medicine, Cumming School of Medicine, Health Research Innovation Center (HRIC), University of Calgary, Room 4C64, 3280 Hospital Drive N.W., Calgary, AB, T2N 4Z6, Canada.
Background: Traumatic brain injury (TBI) is a major public health concern worldwide, contributing to high rates of injury-related death and disability. Severe traumatic brain injury (sTBI), although it accounts for only 10% of all TBI cases, results in a mortality rate of 30-40% and a significant burden of disability in those that survive. This study explored the potential of metabolomics in the diagnosis of sTBI and explored the potential of metabolomics to examine probable primary and secondary brain injury in sTBI.
View Article and Find Full Text PDFEur J Med Res
January 2025
Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Road 2, Guangzhou, 510080, Guangdong, China.
Background: Dementia is a growing public health concern with limited effective treatments. Diet may be a modifiable factor that significantly impacts brain health. Mediterranean diet (MeDi) has been suggested to be associated with brain Magnetic Resonance Imaging (MRI) markers related to dementia, but the existing evidence is inconsistent.
View Article and Find Full Text PDFBMC Musculoskelet Disord
January 2025
Department of Orthopaedics and Traumatology, Ankara Bilkent City Hospital, University of Health Sciences, Ankara, Turkey.
Background: Artcure diffusional patch (ADP) is a novel transdermal therapeutic system that started to be used in the last decade for lumbar disc herniation (LDH). Previous studies have reported early results of the therapy. In this study, we aimed to evaluate the medium- to long-term functional outcomes of this treatment in LDH patients and examine factors predicting the need for surgery after treatment.
View Article and Find Full Text PDFJ Mol Neurosci
January 2025
Bio-Med Big Data Center, CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Alzheimer's disease (AD) is a neurodegenerative disease with no effective treatment, often preceded by mild cognitive impairment (MCI). Multimodal imaging genetics integrates imaging and genetic data to gain a deeper understanding of disease progression and individual variations. This study focuses on exploring the mechanisms that drive the transition from normal cognition to MCI and ultimately to AD.
View Article and Find Full Text PDFMol Imaging Biol
January 2025
Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211, Geneva, Switzerland.
Purpose: We aim to perform radiogenomic profiling of breast cancer tumors using dynamic contrast magnetic resonance imaging (MRI) for the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) genes.
Methods: The dataset used in the current study consists of imaging data of 922 biopsy-confirmed invasive breast cancer patients with ER, PR, and HER2 gene mutation status. Breast MR images, including a T1-weighted pre-contrast sequence and three post-contrast sequences, were enrolled for analysis.
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