New isolates from leaves of and their biological activities.

Nat Prod Res

a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.

Published: June 2019

Three new isolates (-) including one new sterol and two new flavonoids together with three known sterols (-) were isolated from the leaves of . Their structures were determined mainly by spectroscopic methods, including extensive 1D and 2D NMR techniques. All compounds were evaluated for their anti-tobacco mosaic virus and cytotoxic activities. The results showed that compounds and exhibited high anti-TMV activity with inhibition rate of 34.2 and 33.4%, respectively, which were roughly equivalent to that of positive control. The cytotoxicities of compounds and - against five human tumour cell lines were also tested, and tested compounds showed weak inhibitory activities against some tested human tumour cell lines.

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http://dx.doi.org/10.1080/14786419.2018.1425840DOI Listing

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