The Veterans Health Administration is implementing a pragmatic trial research program, called Point of Care Research (POC-R). The purpose of this telephone survey in which respondents were randomized to different framing conditions of the purpose of POC-R was to determine the impact of differing frames of the purpose of POC-R on attitudes towards the program and intentions to participate; and the relative importance of different beliefs and attitudes in discriminating low vs. high intenders to participate in POC-R. The survey addressed veterans' perceptions and attitudes towards POC-R, and their willingness to participate in a pragmatic trial. Overall, respondents felt positively towards POC-R and intended to participate. Differing frames of the purpose of POC-R were not associated with either attitudes (towards the program) or intentions to participate. However, specific beliefs and attitudes toward POC-R program were predictive of intentions to participate.
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http://dx.doi.org/10.1016/j.ssmph.2016.02.005 | DOI Listing |
JAMA Netw Open
January 2025
Latin American Cooperative Oncology Group (LACOG), Porto Alegre, Brazil.
Importance: The open-label randomized phase 2 LACOG0415 trial evaluated 3 treatment strategies for patients with advanced castration-sensitive prostate cancer (CSPC): androgen deprivation therapy (ADT) plus abiraterone acetate and prednisone (AAP), apalutamide (APA) alone, or APA plus AAP.
Objective: To investigate the association of ADT plus AAP, APA alone, or APA plus AAP with health-related quality of life (HRQOL) in patients with advanced CSPC in the LACOG0415 trial.
Design, Setting, And Participants: The LACOG0415 randomized clinical trial comprised 128 patients with advanced CSPC who were randomized (1:1:1) to 1 of 3 treatment arms from October 16, 2017, to April 23, 2019.
J Exp Psychol Gen
January 2025
Department of Psychology, University of Southern California.
Does aligning misinformation content with individuals' core moral values facilitate its spread? We investigate this question in three behavioral experiments ( = 615; = 505; ₂ = 533) that examine how the alignment of audience values and misinformation framing affects sharing behavior, in conjunction with analyzing real-world Twitter data ( = 20,235; 809,414 tweets) that explores how aligning the moral values of message senders with misinformation content influences its dissemination in the context of COVID-19 vaccination misinformation. First, we investigate how aligning messages' moral framing with participants' moral values impacts participants' intentions to share true and false news headlines and whether this effect is driven by a lack of analytical thinking. Our results show that framing a post such that it aligns with audiences' moral values leads to increased sharing intentions, independent of headline familiarity, and participants' political ideology but find no effect of analytical thinking.
View Article and Find Full Text PDFPsilocybin-assisted therapy (PAT) is an experimental treatment with transformative promise. Developing standards for PAT psychotherapy protocols is a priority, but psychotherapeutic protocol components of PAT have been subjected to little rigorous research. This study was designed to assess protocol components in a trial of PAT.
View Article and Find Full Text PDFCureus
December 2024
Neurological Surgery, Jersey Shore Medical Center, Neptune, USA.
Introduction The Synaptive magnetic resonance imaging (MRI) system (Synaptive Medical, Toronto, Canada) is a midfield 0.5 T head-only scanner for imaging the head and neck in adults and pediatrics. The system received US FDA and Health Canada clearance for clinical use in 2020.
View Article and Find Full Text PDFVaccine X
January 2025
Minpapi Association, Tokyo, Japan.
Background: The Human Papillomavirus (HPV) vaccination rate among Japanese high school girls remains critically low, reflecting ongoing public apprehension and misinformation. This study explores the relationship between information presentation and attitudes toward HPV vaccination in Japan.
Methods: We conducted a web-based survey of female high school students aged 15 to 16 and mothers of daughters of similar age across Japan.
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