The steadily increasing size of scientific Monte Carlo simulations and the desire for robust, correct, and reproducible results necessitates rigorous testing procedures for scientific simulations in order to detect numerical problems and programming bugs. However, the testing paradigms developed for deterministic algorithms have proven to be ill suited for stochastic algorithms. In this paper we demonstrate explicitly how the technique of statistical hypothesis testing, which is in wide use in other fields of science, can be used to devise automatic and reliable tests for Monte Carlo methods, and we show that these tests are able to detect some of the common problems encountered in stochastic scientific simulations. We argue that hypothesis testing should become part of the standard testing toolkit for scientific simulations.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1103/PhysRevE.96.053303 | DOI Listing |
BMC Musculoskelet Disord
January 2025
Department of Regional Health Research, University of Southern Denmark, Campusvej 55, Odense M, 5230, Denmark.
Background: The Knee Outcome Survey - Activities of Daily Living Scale (KOS-ADLS) is a patient-reported outcome measure (PROM) developed to assess symptoms and functional limitations in patients with various knee disorders. The aim of this study was to translate and culturally adapt the KOS-ADLS to Danish and to evaluate the psychometric properties of the Danish version (KOS-ADLS-DK) in patients with anterior cruciate ligament (ACL) injury.
Methods: The KOS-ADLS was translated and culturally adapted to Danish in accordance with recommended guidelines.
BMC Nephrol
January 2025
Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Background And Hypothesis: Gut dysbiosis characterized by an imbalance in pathobionts (Enterobacter, Escherichia and Salmonella) and symbionts (Bifidobacterium, Lactobacillus and Prevotella) can occur during chronic kidney disease (CKD) progression. We evaluated the associations between representative symbionts (Bifidobacterium and Lactobacillus) and pathobionts (Enterobacteriaceae) with kidney function in persons with autosomal dominant polycystic kidney disease (ADPKD).
Methods: In this cross-sectional study, 29 ADPKD patients were matched to 15 controls at a 2:1 ratio.
Sci Rep
January 2025
Department of Experimental Psychology, Ghent University, Ghent, Belgium.
How are arbitrary sequences of verbal information retained and manipulated in working memory? Increasing evidence suggests that serial order in verbal WM is spatially coded and that spatial attention is involved in access and retrieval. Based on the idea that brain areas controlling spatial attention are also involved in oculomotor control, we used eye tracking to reveal how the spatial structure of serial order information is accessed in verbal working memory. In two experiments, participants memorized a sequence of auditory words in the correct order.
View Article and Find Full Text PDFSci Rep
January 2025
College of Civil Engineering, Guizhou University, Huaxi District, Guiyang, 550025, Guizhou, China.
Long-term erosion by acidic solutions in karst regions leads to continuous deterioration of the physical and mechanical properties at the interfaces of engineering structures, adversely affecting their operational performance. To investigate the degradation patterns of the mechanical properties and corrosion mechanisms of the concrete‒limestone composite (CLC) after exposure to acidic corrosion, three kinds of CLC samples treated with acidic solutions of different pH values were fabricated. Mechanical property analysis was conducted via triaxial compression testing methods.
View Article and Find Full Text PDFJ Clin Periodontol
January 2025
Department of Biomedical Sciences, School of Dental Medicine, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.
Introduction: Telomeres are nucleotide sequences found at the end of chromosomes, and their shortening is associated with chronological and biological ageing, oxidative stress and malnutrition. Shorter telomeres have been shown to be associated with periodontitis. Dietary nutrients are also influential factors in the aetiology and progression of periodontitis and other chronic inflammatory diseases.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!