AI Article Synopsis
- Exercise leads to significant physical and metabolic changes in skeletal muscle, allowing it to adapt to current physiological needs.
- These changes are primarily driven by broad alterations in gene expression.
- The nuclear hormone receptor Nor-1 is hypothesized to be activated post-exercise, influencing gene expression to facilitate muscle adaptations related to contractile organization.
Article Abstract
Exercise induces various physical and metabolic changes in skeletal muscle that adaptively reprograms this tissue to current physiological and environmental demands. Underlying these changes are broad modifications to gene expression. We postulate that the nuclear hormone receptor, Nor-1, is activated after exercise, and this transcription factor modifies gene expression to drive the molecular and cellular adaptations associated with contractile reorganization.
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| http://dx.doi.org/10.1249/JES.0000000000000143 | DOI Listing |
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