Natural products and ring-closing metathesis: synthesis of sterically congested olefins.

Nat Prod Rep

Paris Descartes University, Sorbonne Paris Cité, Faculté des Sciences Pharmaceutiques et Biologiques, Unité CNRS UMR 8638 COMÈTE, 4 Avenue de l'observatoire, 75270 Paris Cedex 06, France.

Published: January 2018

Covering: 2002 to August 2017.This review highlights recent RCM reactions towards the synthesis of sterically congested natural products. It offers an insight into various synthetic targets and approaches and provides information on the evolution of catalysts as powerful tools enabling the use of increasingly challenging diene precursors.

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Source
http://dx.doi.org/10.1039/c7np00048kDOI Listing

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