Diffuse spinal arachnoiditis in neurobrucellosis is a rare manifestation. We report a boy aged 17, presenting with hearing impairment and recurrent vomiting for 18 months, weight loss for 12 months, dysphagia, dysarthria, hypophonia for 6 months, and gait unsteadiness for 5 months. He had bilateral 5th (motor) to 12th cranial nerve palsy, wasting and weakness of limbs, fasciculations, absent tendon reflexes, and positive Babinski's sign. Cerebrospinal fluid (CSF) showed raised protein and pleocytosis. Magnetic resonance imaging (MRI) showed extensive enhancing exudates in cisterns and post-contrast enhancement of bilateral 5th, 6th, 7th, and 8th nerves. Spine showed clumping with contrast enhancement of the cauda equina roots and encasement of the cord with exudates. Serum and CSF were positive for anti- antibodies. He showed significant improvement with antibiotics. At 4 months follow-up, MRI demonstrated near complete resolution of cranial and spinal arachnoiditis. It is important to recognize such rare atypical presentations of neurobrucellosis.
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http://dx.doi.org/10.4269/ajtmh.17-0828 | DOI Listing |
World Neurosurg
December 2024
Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, P.R. China. Electronic address:
Introduction: Spinal arachnoiditis (SA) involves chronic inflammation of the spinal arachnoid membrane, often due to surgery, trauma, infections, or autoimmune issues. It leads to ongoing pain and sensory disturbances in the back and lower limbs, along with possible bladder and bowel issues. Treatments focus on symptom relief and improving life quality.
View Article and Find Full Text PDFSpinal Cord Ser Cases
June 2024
Department of Neurology and Neurosurgery, Riga Stradinš University, 16 Dzirciema Street, Riga, LV-1007, Latvia.
Background And Importance: Syringomyelia, or the formation of fluid-filled cysts within the spinal cord, associated with delayed spinal arachnoiditis is an uncommon complication of aneurysmal subarachnoid haemorrhage. To date, about 18 cases have been reported in medical literature, with just two reported in patients under the age of 35 years.
Clinical Presentation: A 27-year-old female patient complained of sudden, severe headaches in the occipital region, nuchal rigidity, and drowsiness when she presented at our institution.
Background: Spinal arachnoiditis can result from various factors, including spinal subarachnoid hemorrhage (sSAH). In this paper, the authors describe a case of intradural extramedullary cavernoma with an initial presentation of subarachnoid hemorrhage leading to multilevel spinal arachnoiditis to discuss the pathophysiology and optimal treatment strategy.
Observations: Spinal intradural extramedullary cavernoma manifesting with sSAH is a rare clinical presentation; therefore, there is no clear strategy for the management of sSAH.
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