Elevated O-GlcNAcylation is emerging as a general characteristic of most cancers. Although O-GlcNAcylation can regulate many cell biological pathways, recent evidence suggests that it is a key regulator of metabolic pathways including glycolysis in cancer cells. This review summarizes our current understanding of how O-GlcNAcylation regulates glycolytic pathways and contributes to alterations in cancer cell metabolism.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386736 | PMC |
| http://dx.doi.org/10.1007/s10863-018-9742-3 | DOI Listing |
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