It is well known that spirostane-type saponins show various bioactivities. In our on-going program of screening these kinds of constituents from natural products, was found to be rich in them, and nine new spirostanol saponins, Yucca spirostanosides A₁ (), A₂ (), B₁ (), B₂ (), B₃ (), C₁ (), C₂ (), C₃ (), and D₁ (), together with five known ones (-) were isolated from the plant. Their structures were elucidated by extensive spectroscopic methods, including 1D and 2D NMR and MS spectra, and comparing with published data.
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http://dx.doi.org/10.3390/molecules23010167 | DOI Listing |
Molecules
July 2024
Food Technology Division, University of Almería, 04120 Almería, Spain.
The shoots of L. are consumed worldwide, although most species belonging to this genus have a restricted range, and several taxa remain unstudied. In this work, a total of four taxa from different locations were scrutinized and compared with cultivated .
View Article and Find Full Text PDFNat Prod Res
January 2025
Department of Biology, Thai Nguyen University of Education, Thai Nguyen, Viet Nam.
Three new minor steroidal glycosides were isolated from the whole plants of (Wall. ex Hornem.) Wight.
View Article and Find Full Text PDFRSC Adv
January 2022
Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University Mansoura 35516 Egypt
Bioassay-guided investigation of extract resulted in the identification of seven steroidal saponins (Turgidosterones 1-7). They were evaluated for their antifungal, antileishmanial, and antitrypanosomal activities. Turgidosterone 6 was the most active antifungal against and (IC values of 2.
View Article and Find Full Text PDFFitoterapia
September 2020
State Key Laboratory of Phytochemistry and Plant Resources in West China and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address:
Based on a method combining the LC-MS/MS molecular networking strategy with the conventional means of phytochemical research, the chemical constituents and the availability of Paris tengchongensis, a new species found in 2017 from Yunnan Province, were investigated for the first time. The molecular networking showed that this species contained the characteristic steroidal glycosides of the genus Paris by comparison of those of Paris polyphylla var. yunnanensis.
View Article and Find Full Text PDFJ Pharm Biomed Anal
April 2019
National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS, 38677, USA; Division of Pharmacognosy, Department of BioMolecular Sciences, School of Pharmacy, The University of Mississippi, MS 38677, USA. Electronic address:
A previously unidentified purported botanical ingredient was found in dietary supplements marketed for anabolic benefits. In an attempt to assess the 'naturalness' of a group of steroid-like compounds called laxogenins, a UHPLC-QToF method was developed. Several dietary supplements claim to contain 5α-hydroxy laxogenin, which is a derivative of a naturally occurring spirostane-type steroid, laxogenin.
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