Early learning experiences shape the development of the behavioral constellation of deprivation (BCD) proposed by Pepper & Nettle (P&N). There is considerable variability in early learning experiences across diverse socioeconomic status (SES) backgrounds, particularly when it comes to language. Here, we discuss how early learning experiences are beyond the control of the individual and subsequently contribute to behaviors in P&N's constellation.
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http://dx.doi.org/10.1017/S0140525X17001017 | DOI Listing |
Front Sports Act Living
January 2025
Department of Sports Science, Sichuan University, Chengdu, China.
Background: In recent years, an increasing number of scholars have begun to focus on the relationship between children's motor development and school activities, with the relationship between children's fine motor skills and academic achievement being a particularly researched area. However, due to different research perspectives among scholars, the results in this field have been somewhat controversial. Therefore, this study aims to delve deeper into the relationship between children's fine motor skills and their various academic abilities through systematic review and meta-analysis.
View Article and Find Full Text PDFBMJ Neurol Open
January 2025
Neurological Surgery, Mount Sinai Health System, New York, New York, USA.
Background: Early diagnosis of degenerative cervical myelopathy (DCM) is often challenging due to subtle, non-specific symptoms, limited disease awareness and a lack of definitive diagnostic criteria. As primary care physicians are typically the first to encounter patients with early DCM, equipping them with effective screening tools is crucial for reducing diagnostic delays and improving patient outcomes. This systematic review evaluates the efficacy of quantitative screening methods for DCM that can be implemented in primary care settings.
View Article and Find Full Text PDFComput Struct Biotechnol J
December 2024
Key Laboratory of Systems Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China.
Persistent infection with high-risk human papillomavirus (hrHPV) is a major cause of cervical cancer. The effectiveness of current HPV-DNA testing, which is crucial for early detection, is limited in several aspects, including low sensitivity, accuracy issues, and the inability to perform comprehensive hrHPV typing. To address these limitations, we introduce MTIOT (Multiple subTypes In One Time), a novel detection method that utilizes machine learning with a new multichannel integration scheme to enhance HPV-DNA analysis.
View Article and Find Full Text PDFFront Neurosci
January 2025
Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea.
Introduction: Delirium, frequently experienced by ischemic stroke patients, is one of the most common neuropsychiatric syndromes reported in the Intensive Care Unit (ICU). Stroke patients with delirium have a high mortality rate and lengthy hospitalization. For these reasons, early diagnosis of delirium in the ICU is critical for better patient prognosis.
View Article and Find Full Text PDFFront Pharmacol
January 2025
Department of General Surgery, The Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, China.
Background: Pancreatic cancer remains one of the deadliest malignancies, largely due to its late diagnosis and lack of effective therapeutic targets.
Materials And Methods: Using traditional machine learning methods, including random-effects meta-analysis and forward-search optimization, we developed a robust signature validated across 14 publicly available datasets, achieving a summary AUC of 0.99 in training datasets and 0.
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