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Racial Trauma and Black Mothers' Mental Health: Does Cognitive Flexibility Buffer the Effects of Racialized Stress?
J Racial Ethn Health Disparities
January 2025
Department of Biobehavioral Health, The Pennsylvania State University, 219 Biobehavioral Health Bldg, University Park, PA, 16802, USA.
Racialized stress disproportionately impacts Black individuals and confers increased risk for psychological distress and executive dysfunction. However, there is little evidence on psychological distress' association with cognitive flexibility (CF), an executive function theorized to be a neurocognitive resilience factor, as it is shown to reflect the ability to adapt thoughts/behaviors to changing environmental stimuli. As such, we aimed to examine the relation between racialized stress and psychological distress and the potential buffering effects of CF.
View Article and Find Full Text PDFGlobal, regional, and national trends in type 2 diabetes mellitus burden among adolescents and young adults aged 10-24 years from 1990 to 2021: a trend analysis from the Global Burden of Disease Study 2021.
World J Pediatr
January 2025
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
Background: Type 2 diabetes mellitus (T2DM) poses an escalating public health challenge among adolescents and young adults worldwide. Despite the rising incidence, comprehensive data on the burden and trends of T2DM in this demographic remain scarce. This study aims to evaluate the burden of T2DM among individuals aged 10-24 years globally, regionally, and nationally from 1990 to 2021.
View Article and Find Full Text PDFPromoting emotional well-being (EWB) in older adults at risk for Alzheimer's Disease (AD), for example those with mild behavioral impairment (MBI), mild cognitive impairment (MCI), or subjective cognitive decline (SCD), is important both to improve quality of life and slow the progress of cognitive decline. Understanding how the early accumulation of AD pathology affects EWB and developing interventions to improve EWB both require the precise measurement of affective experience that plays a key role in EWB. Day to day affective experiences, both positive and negative, contribute significantly to EWB, but how affective experience maps onto EWB is complex.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
University of Calgary, Calgary, AB, Canada.
Background: Mild behavioral impairment (MBI) is a syndrome that leverages neuropsychiatric symptoms that emerge in later-life, and which persist, to identify individuals at high-risk for incident dementia. Attendant with MBI are changes in quality of life (QoL), which can present concurrent with the onset of cognitive decline or even before. Obtaining information from participants and study partners can provide a broader overview of health and QoL.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
University of Exeter, Exeter, United Kingdom.
Background: When assessed in the Mild Behavioral Impairment (MBI) framework, late-life onset psychotic like symptoms (MBI-psychosis) are associated with incident cognitive decline and dementia. One approach to examining the genetic basis of this association, is to use Polygenic Risk Scores (PRS) to determine whether genetic propensity for late-life onset psychosis is shared with other traits. We aimed to elucidate the shared genetic liability between Educational Attainment, Intelligence, Reasoning, Memory, Neuroticism, Alzheimer's Disease, Major Depression, Schizophrenia and Bipolar Disorder and Mild Behavioral Impairment (MBI)-Psychosis in later life.
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