It was established that plasma level of beta-endorphin-like IR in baboons (Papio hamadryas) was 8 +/- 1 fM/ml, and of beta-lipoprotein-like IR- 9 +/- 1 fM/ml. Ratio between beta-endorphin-like and beta-lipoprotein-like IR was 0.9 +/- 0.1. Under the electrical stimulation of the periventricular-perifornical area of hypothalamus, the level of beta EP-IR reached 26 +/- 9 fM/ml while the level of beta LP-IR fell. On the mamillary hypothalamic area stimulating, no similar changes were observed. A considerable increase in the beta EP-IR level, up to 53 +/- 2 fM/ml, was recorded in hemorrhagic shock. Levels of plasma beta EP-IR in baboons and in men are concluded to be close and the increase of them associated with the stress status of baboons.

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