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The increasing incidence and mortality of bacteremia in Denmark from 2010 to 2022: a population-based nationwide cohort study.
Front Public Health
January 2025
Department of Veterinary and Animal Science, Faculty of Health, University of Copenhagen, Copenhagen, Denmark.
Objectives: An increasing incidence of positive blood cultures has been reported in several countries. This represents an important challenge for public health due to the large number of hospital admissions with high mortality among these patients. This study aims to characterize the epidemiology and mortality associated with positive blood cultures.
View Article and Find Full Text PDFInvestigating the time to blood culture positivity: why does it take so long?
J Med Microbiol
January 2025
Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK.
Bloodstream infections (BSIs) are one of the most serious infections investigated by microbiologists. However, the time to detect a BSI fails to meet the rapidity required to inform clinical decisions in real time. Blood culture (BC) is considered the gold standard for diagnosing bloodstream infections.
View Article and Find Full Text PDFOptimizing Management of Febrile Young Infants Without Serum Procalcitonin.
Pediatrics
January 2025
Departments of Pediatrics and Emergency Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC.
Background: Febrile young infants are at risk of invasive bacterial infections (IBIs; bacteremia or bacterial meningitis). American Academy of Pediatrics (AAP) guidelines recommend that when procalcitonin testing is unavailable, C-reactive protein (CRP), absolute neutrophil count (ANC) and temperature should be used to identify low-risk infants. We sought to determine the optimal combination of these inflammatory markers to predict IBI when procalcitonin is unavailable.
View Article and Find Full Text PDFInterrater reliability and agreement of the NEUMOBACT checklist about infection-prevention performance of intensive care nurses in simulation-based scenarios.
PLoS One
December 2024
Department of Fundamental and Clinical Care Nursing, Hospitalet del Llobregat, Universitat de Barcelona, Campus de Bellvitge, Barcelona, Spain.
Objective: To analyse the interrater reliability of the NEUMOBACT checklist and verify whether consistent results are reproducible.
Methods: A validation study with a cross-sectional design, compliant with the GRRAS checklist, among ICU nurses attending a SIMULAZERO course with an Objective Structured Clinical Evaluation simulation format, to verify transfer from theory to clinical practice of knowledge and skills in ventilator-associated pneumonia (VAP) and catheter-related bacteraemia (CRB) prevention. A minimum sample size of 111 pairs of nurse raters was calculated.
Mandatory surveillance of bacteremia conducted by automated monitoring.
Front Public Health
December 2024
Department of Data Integration and Analysis, Statens Serum Institut, Copenhagen, Denmark.
Except for a few countries, comprehensive all-cause surveillance for bacteremia is not part of mandatory routine public health surveillance. We argue that time has come to include automated surveillance for bacteremia in the national surveillance systems, and explore diverse approaches and challenges in establishing bacteremia monitoring. Assessed against proposed criteria, surveillance for bacteremia should be given high priority.
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