Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770017PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190540PLOS

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