AI Article Synopsis
- This paper discusses a new method for storing clinical microdialysis samples using tubing, providing better options for delayed analysis compared to traditional sampling methods.
- Samples stored in this tubing remain stable for up to 72 days when kept at -80 °C, allowing for consistent results over time.
- The authors present a general model to help choose the right tubing parameters based on storage time and flow rate, ensuring effective performance without causing leaks in the microdialysis probe.
Article Abstract
This paper presents the use of tubing to store clinical microdialysis samples for delayed analysis with high temporal resolution, offering an alternative to traditional discrete offline microdialysis sampling. Samples stored in this way were found to be stable for up to 72 days at -80 °C. Examples of how this methodology can be applied to glucose and lactate measurement in a wide range of in vivo monitoring experiments are presented. This paper presents a general model, which allows for an informed choice of tubing parameters for a given storage time and flow rate avoiding high back pressure, which would otherwise cause the microdialysis probe to leak, while maximising temporal resolution.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804479 | PMC |
| http://dx.doi.org/10.1039/c7an01209h | DOI Listing |
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