Purpose: Many studies reporting dental utilization under general anesthesia (GA) are dated. The purpose of this study was to provide contemporaneous data about children receiving dental GA by: (1) determining trends in utilization and associated expenditures; and (2) examining the effects of provider distribution.
Methods: This time series cross-sectional study of Medicaid-eligible children ages zero to eight years old in North Carolina used aggregate Medicaid claims from State Fiscal Years (SFY) 2011 to 2015 to collect demographic and dental treatment information. Descriptive statistics were stratified by age and year to examine trends over time. Panel analysis techniques were used to explore regional effects of provider distribution on dental GA utilization.
Results: For SFY 2011 to 2015, the overall dental utilization rate was 517.1 per 1,000 (total enrolled equals 632,941 children/year), and the dental GA utilization rate was 15.8 per 1,000. Total dental expenditures averaged $113 million per year, and dental GA averaged $16.7 million per year. The dental GA proportion of expenditures increased over time (P<.001). Provider distribution did not affect dental GA utilization rate (P=.178) but did increase the number of children receiving dental GA (P<.001).
Conclusions: Utilization and expenditures associated with dental treatment under general anesthesia continue to increase. While this reflects increased access to care, interventions should be examined to provide preventive care earlier in a child's life.
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Eur J Dent
March 2025
Department of Molecular Biology and Biochemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Objective: The goal is to analyze the osteogenesis potential of polymethylmethacrylate (PMMA)-hydroxyapatite (HA) and stem cells from human exfoliated deciduous teeth (SHED) as a biomaterial candidate for alveolar bone defect therapy through a bioinformatic approach within an study.
Materials And Methods: Three-dimensional (3D) ligand structures consisting of HA, PMMA, and target proteins of SHED were obtained from the PubChem database. STITCH was used for SHED target protein analysis, STRING was utilized for analysis and visualization of protein pathways related to osteogenesis, PASS Online was employed to predict biological functions supporting osteogenesis potential, PyRx 0.
Eur J Dent
March 2025
Department of Community Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Objectives: This study aims to explore the beliefs and attitudes related to the adoption of teledentistry among Pakistani dental professionals, focusing on data security, practice enhancement, and patient benefits.
Material And Methods: A cross-sectional study on a 5-point Likert scale assessed four domains of teledentistry: data security and patient consent, practice improvement capabilities, usefulness for dental practice, and patient benefits, among dental professionals through electronic forms. Demographic data and items from four domains were analyzed by descriptive statistics, analysis of variance and Pearson's correlation tests, respectively, using SPSS, with a -value of < 0.
Biochim Biophys Acta Mol Basis Dis
March 2025
Karachi Institute of Biotechnology and Genetic Engineering (KIBGE), University of Karachi, Karachi, Sindh, Pakistan. Electronic address:
Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised by inflammatory synovial tissue, joint deterioration, and effects on systems other than the joints. The biological process underlying the progression of the disease remains unknown, however cell-mediated immunity plays an important part in the onset of RA. The current study investigated the involvement of the JAK-STAT pathway genes (JAK-1, IL-6, and SOCS-2) in the pathogenesis of RA (Rheumatoid arthritis).
View Article and Find Full Text PDFComput Biol Med
March 2025
Department of Oral Implantology, Peking University School and Hospital of Stomatology, Beijing, 100081, China; National Center of Stomatology, National Clinical Research Center for Oral Disease, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, Beijing, 100081, China. Electronic address:
With the ongoing advancement of digital technology, oral medicine transitions from traditional diagnostics to computer-assisted diagnosis and treatment. Identifying dental implants in patients without records is complex and time-consuming. Accurate identification of dental implants is crucial for ensuring the sustainability and reliability of implant treatment, particularly in cases where patients lack available medical records.
View Article and Find Full Text PDFTissue Eng Regen Med
March 2025
Department of Chemical Engineering, Kwangwoon University, 20 Kwangwoon-Ro, Nowon-Gu, Seoul, 01897, Republic of Korea.
Background: Strontium ranelate (SR) is an effective bone regeneration drug; however, its low bioavailability and strong hydrophilicity cause a strong cytotoxicity, venous thrombosis, and allergic reactions when administered in its free form. This study aims to enhance the SR bioavailability by utilizing nanostructured lipid carriers (NLC) as a drug delivery system (DDS).
Methods: To improve the drug delivery efficiency and sustained release of the NLC, their surfaces were coated with chitosan oligosaccharide (COS), a natural polymer.
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