AI Article Synopsis
- Central diabetes insipidus is a rare condition in children caused by a lack of vasopressin, leading to symptoms like excessive urination and thirst.
- One major cause of this condition in children is brain malformations, such as hydranencephaly.
- The synthetic drug desmopressin, often administered sublingually, has proven effective in treating infants with this condition, as demonstrated by two cases.
Article Abstract
Central diabetes insipidus is a rare disease in children caused by a deficiency of vasopressin. Its main clinical manifestations are polyuria and polydipsia. Brain malformations are one of the main causes. Desmopressin is the synthetic drug of choice for the treatment. One of the routes of administration is sublingual and its use in infants is very limited. We describe two infants with central diabetes insipidus and hydranencephaly who were successfully treated with sublingual desmopressin.
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| http://dx.doi.org/10.5546/aap.2018.e93 | DOI Listing |
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