The value of medical laboratory testing is often directed to the cost of testing however the clinical benefits of these tests are at least as important. Laboratory testing has an acknowledged widespread role in clinical decision making, and therefore a role in determining clinical outcome. Consequently, the value of laboratory testing should be considered in its role in affecting beneficial actions and outcomes. This includes both the requesting phase of choosing tests which will influence clinical decision making as well as the reporting phase in a way that guides clinical decisions and actions. Clinical decision support systems and software can enhance the value of medical laboratory testing if they are directed toward facilitating those clinical decisions where there is either evidence, or agreed consensus, addressing patient outcomes.
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Mol Ecol
December 2024
Department of Botany, University of Wyoming, Laramie, Wyoming, USA.
Adaptive radiations are rich laboratories for exploring, testing, and understanding key theories in evolution and ecology because they offer spectacular displays of speciation and ecological adaptation. Particular challenges to the study of adaptive radiation include high levels of species richness, rapid speciation, and gene flow between species. Over the last decade, high-throughput sequencing technologies and access to population genomic data have lessened these challenges by enabling the analysis of samples from many individual organisms at whole-genome scales.
View Article and Find Full Text PDFIJID Reg
March 2025
Regional Level Viral Research & Diagnostic Laboratory (RVRDL), Department of Microbiology, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry, India.
Objectives: Human metapneumovirus (hMPV) is recognized as a significant cause of acute respiratory infections among infants under 5 years of age.
Methods: Nasal swabs collected from January 2021 to June 2024 were screened to detect hMPV using reverse transcription-quantitative polymerase chain reaction. Furthermore, representative positive samples were sequenced and subjected to phylogenetic analysis.
IJID Reg
March 2025
Corporate Quality and Patient Safety Department, Hamad Medical Corporation, Doha, Qatar.
Objectives: Mass gathering events may facilitate the transmission of foodborne diseases. We determined the presentations and causative organisms of gastrointestinal illness among the attendees of the Fédération Internationale de Football Association Football World Cup 2022 (FIFA 2022).
Methods: The study was conducted at Hamad Medical Corporation in Qatar, which served as the national reference laboratory for all microbiology testing.
While zinc-ion and hybrid aqueous battery systems have emerged as potential substitutes for expensive lithium-ion batteries, issues like side reactions, limited electrochemical stability, and electrolyte leakage hinder their commercialization. Due to their low cost, high stability, minimal leakage risks, and a wide variety of modification opportunities, hydrogel electrolytes are considered the most promising solution compared to liquid or solid electrolytes. Here, we synthesized a dual-function hydrogel electrolyte based on polyacrylamide and poly(ethylene dioxythiophene):polystyrene (PPP).
View Article and Find Full Text PDFVirus Evol
December 2024
Department of Ecology and Evolutionary Biology, Yale University, 165 Prospect Street, New Haven, CT 06511, United States.
Different theoretical frameworks have been invoked to guide the study of virus evolution. Three of the more prominent ones are (i) the evolution of virulence, (ii) life history theory, and (iii) the generalism-specialism dichotomy. All involve purported tradeoffs between traits that define the evolvability and constraint of virus-associated phenotypes.
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